SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lhk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3lhk PUTATIVE DNA BINDING
PROTEIN MJ0014
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  97
LEU A 117
VAL A 121
LEU A 137
ILE A 131
 None
 1.11A 3gwxB-3lhkA:
undetectable		 3gwxB-3lhkA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3lhk PUTATIVE DNA BINDING
PROTEIN MJ0014
(Methanocaldococc
us
jannaschii) 		4 / 6 GLY A 106
THR A 138
LEU A 137
ASP A 102
 None
 0.96A 3ps9A-3lhkA:
2.6		 3ps9A-3lhkA:
13.10