SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		3 / 3 TRP A 154
THR A  20
TYR A  16
 None
 1.19A 2a3aA-3lhoA:
undetectable		 2a3aA-3lhoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		3 / 3 TRP A 154
THR A  20
TYR A  16
 None
 1.13A 2a3aB-3lhoA:
undetectable		 2a3aB-3lhoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		3 / 3 TRP A 154
THR A  20
TYR A  16
 None
 1.20A 2a3bA-3lhoA:
undetectable		 2a3bA-3lhoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		4 / 6 LEU A  12
PHE A   9
ILE A  41
PHE A 235
 None
 0.89A 3ko0B-3lhoA:
undetectable		 3ko0B-3lhoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		4 / 6 LEU A  12
PHE A   9
ILE A  41
PHE A 235
 None
 0.95A 3ko0S-3lhoA:
undetectable		 3ko0S-3lhoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		5 / 9 TYR A 160
ILE A 115
ILE A 111
VAL A  51
THR A  45
 None
 1.43A 3p4wA-3lhoA:
undetectable		 3p4wA-3lhoA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		4 / 6 ILE A  79
LEU A  53
ILE A  95
TYR A 151
 None
 0.83A 5mvmB-3lhoA:
undetectable
5mvmC-3lhoA:
undetectable		 5mvmB-3lhoA:
15.53
5mvmC-3lhoA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		5 / 10 TYR A 160
ILE A 115
ILE A 111
VAL A  51
THR A  45
 None
 1.39A 5mvnD-3lhoA:
undetectable		 5mvnD-3lhoA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3lho PUTATIVE HYDROLASE
(Shewanella
frigidimarina) 		4 / 7 PHE A 175
ARG A 237
ALA A 184
GLN A 187
 None
 0.98A 6b89A-3lhoA:
undetectable		 6b89A-3lhoA:
13.85