SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 8 LEU A 109
ASP A  18
LEU A  17
LEU A  21
 None
 1.01A 1e7cA-3lhqA:
3.5		 1e7cA-3lhqA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 5 THR A  12
VAL A  19
LEU A  23
GLN A  26
 None
 0.69A 1fbmE-3lhqA:
undetectable		 1fbmE-3lhqA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 7 PHE A  24
LEU A  34
MET A 123
VAL A 124
 None
 0.97A 1wrlA-3lhqA:
undetectable
1wrlB-3lhqA:
undetectable		 1wrlA-3lhqA:
17.67
1wrlB-3lhqA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 5 LEU A 199
LEU A 198
LEU A 208
CYH A 148
 None
 0.96A 2ab2B-3lhqA:
undetectable		 2ab2B-3lhqA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		5 / 12 ALA A 129
VAL A 126
PHE A  59
LEU A  21
LEU A  17
 None
 1.29A 3b0wB-3lhqA:
undetectable		 3b0wB-3lhqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		3 / 3 CYH A 117
LYS A 116
HIS A 115
 None
 0.89A 5js5A-3lhqA:
2.2		 5js5A-3lhqA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 5 LEU A 159
ALA A 163
LEU A 166
LEU A 145
 None
 0.86A 5vkqA-3lhqA:
undetectable
5vkqD-3lhqA:
undetectable		 5vkqA-3lhqA:
9.17
5vkqD-3lhqA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 5 LEU A 145
LEU A 159
ALA A 163
LEU A 166
 None
 0.86A 5vkqA-3lhqA:
undetectable
5vkqB-3lhqA:
undetectable		 5vkqA-3lhqA:
9.17
5vkqB-3lhqA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3lhq ACRAB OPERON
REPRESSOR (TETR/ACRR
FAMILY)
(Salmonella
enterica) 		4 / 5 LEU A 145
LEU A 159
ALA A 163
LEU A 166
 None
 0.82A 5vkqB-3lhqA:
undetectable
5vkqC-3lhqA:
undetectable		 5vkqB-3lhqA:
9.17
5vkqC-3lhqA:
9.17