SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lhr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 3lhr ZINC FINGER PROTEIN
24
(Homo
sapiens) 		4 / 8 PRO A  74
GLU A  79
GLU A  85
ASP A  86
 None
 0.97A 1dtlA-3lhrA:
undetectable		 1dtlA-3lhrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 3lhr ZINC FINGER PROTEIN
24
(Homo
sapiens) 		4 / 5 GLN A  56
ALA A  59
GLN A  66
ILE A  60
 None
 1.17A 2z0aA-3lhrA:
undetectable		 2z0aA-3lhrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3lhr ZINC FINGER PROTEIN
24
(Homo
sapiens) 		4 / 5 LYS A  45
GLN A  47
LEU A  49
GLU A  50
 None
None
EMC  A  97 (-3.5A)
EMC  A  97 (-4.0A)
 0.90A 3h5gA-3lhrA:
undetectable
3h5gB-3lhrA:
undetectable		 3h5gA-3lhrA:
17.78
3h5gB-3lhrA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3lhr ZINC FINGER PROTEIN
24
(Homo
sapiens) 		4 / 6 LYS A  45
GLN A  47
LEU A  49
GLU A  50
 None
None
EMC  A  97 (-3.5A)
EMC  A  97 (-4.0A)
 1.09A 3h5gB-3lhrA:
undetectable
3h5gC-3lhrA:
undetectable		 3h5gB-3lhrA:
17.78
3h5gC-3lhrA:
17.78