SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lhx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 7 GLY A 372
ARG A 171
ILE A 163
TYR A 161
GLY A 100
 None
 1.39A 11gsB-3lhxA:
undetectable		 11gsB-3lhxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 303
ALA A 335
GLY A 336
HIS A 361
ALA A 364
ILE A 368
 None
 0.64A 1bx4A-3lhxA:
31.2		 1bx4A-3lhxA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		4 / 5 GLU A 228
LEU A 222
LEU A 225
LEU A 223
 None
 0.98A 1np1A-3lhxA:
undetectable		 1np1A-3lhxA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		4 / 5 LEU A 211
LEU A 206
LEU A 198
MET A 260
 None
 1.05A 2oaxF-3lhxA:
undetectable		 2oaxF-3lhxA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		4 / 7 THR A 103
MET A 136
ASP A 102
SER A 210
 None
 1.18A 2xytI-3lhxA:
undetectable		 2xytI-3lhxA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 9 GLY A 372
ARG A 171
ILE A 163
TYR A 161
GLY A 100
 None
 1.40A 3csjB-3lhxA:
undetectable		 3csjB-3lhxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		3 / 3 SER A 210
ASP A 102
ASN A 105
 None
 0.84A 3lsfB-3lhxA:
undetectable
3lsfE-3lhxA:
undetectable		 3lsfB-3lhxA:
22.33
3lsfE-3lhxA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		3 / 3 ASP A 102
ASN A 105
SER A 210
 None
 0.79A 3lsfB-3lhxA:
undetectable
3lsfE-3lhxA:
undetectable		 3lsfB-3lhxA:
22.33
3lsfE-3lhxA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		3 / 3 ASP A 102
ASN A 105
SER A 210
 None
 0.85A 3lslA-3lhxA:
1.5
3lslD-3lhxA:
undetectable		 3lslA-3lhxA:
22.01
3lslD-3lhxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		3 / 3 SER A 210
ASP A 102
ASN A 105
 None
 0.79A 3lslA-3lhxA:
1.5
3lslD-3lhxA:
undetectable		 3lslA-3lhxA:
22.01
3lslD-3lhxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 3uboB-3lhxA:
30.5		 3uboB-3lhxA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		3 / 3 ASP A 102
GLU A  83
GLY A  82
 None
 0.59A 3w9tA-3lhxA:
undetectable		 3w9tA-3lhxA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.54A 4e3aA-3lhxA:
30.3		 4e3aA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.57A 4e3aB-3lhxA:
30.3		 4e3aB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4jksA-3lhxA:
30.4		 4jksA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4jksB-3lhxA:
30.5		 4jksB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.50A 4jkuA-3lhxA:
30.6		 4jkuA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4jkuB-3lhxA:
30.6		 4jkuB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k8cA-3lhxA:
30.4		 4k8cA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4k8cB-3lhxA:
30.4		 4k8cB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k8kA-3lhxA:
30.4		 4k8kA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k8kB-3lhxA:
30.5		 4k8kB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4k8pA-3lhxA:
30.5		 4k8pA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4k8pB-3lhxA:
30.4		 4k8pB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4k8tA-3lhxA:
30.5		 4k8tA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k8tB-3lhxA:
30.5		 4k8tB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k93A-3lhxA:
30.5		 4k93A-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4k93B-3lhxA:
30.5		 4k93B-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 100
GLY A 101
ASN A 105
LEU A 246
THR A 333
ASP A 337
 None
 1.42A 4k9cA-3lhxA:
30.4		 4k9cA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 100
GLY A 101
ASN A 105
LEU A 246
THR A 333
ASP A 337
 None
 1.41A 4k9cB-3lhxA:
30.4		 4k9cB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k9iA-3lhxA:
30.5		 4k9iA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4k9iB-3lhxA:
30.4		 4k9iB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 100
GLY A 101
ASN A 105
LEU A 246
THR A 333
ASP A 337
 None
 1.42A 4kadA-3lhxA:
30.6		 4kadA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4kadB-3lhxA:
29.5		 4kadB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4kahA-3lhxA:
30.5		 4kahA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4kahB-3lhxA:
30.5		 4kahB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4kalA-3lhxA:
30.5		 4kalA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4kalB-3lhxA:
30.5		 4kalB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4kanA-3lhxA:
30.4		 4kanA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4kanB-3lhxA:
30.5		 4kanB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.50A 4kbeA-3lhxA:
30.5		 4kbeA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4kbeB-3lhxA:
30.5		 4kbeB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lbgA-3lhxA:
30.5		 4lbgA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 10 ALA A 321
VAL A 329
ALA A 335
ALA A 364
ILE A 368
 None
 0.48A 4lbgA-3lhxA:
30.5		 4lbgA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lbgB-3lhxA:
30.4		 4lbgB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 9 ALA A 321
VAL A 329
ALA A 335
ALA A 364
ILE A 368
 None
 0.54A 4lbgB-3lhxA:
30.4		 4lbgB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.52A 4lbxA-3lhxA:
30.4		 4lbxA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lbxB-3lhxA:
30.4		 4lbxB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lc4A-3lhxA:
30.4		 4lc4A-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lc4B-3lhxA:
30.5		 4lc4B-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.53A 4lcaA-3lhxA:
30.4		 4lcaA-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 100
GLY A 101
ASN A 105
THR A 333
ASP A 337
 None
 0.51A 4lcaB-3lhxA:
30.5		 4lcaB-3lhxA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		4 / 8 PHE A  99
VAL A 145
TYR A 123
ALA A 111
 None
 0.79A 4m48A-3lhxA:
undetectable		 4m48A-3lhxA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 8 SER A 210
LEU A 204
VAL A 236
ILE A 237
MET A 260
 None
 1.46A 4oj4A-3lhxA:
undetectable		 4oj4A-3lhxA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 11 LEU A 186
TRP A 185
ILE A 194
GLU A 228
LEU A 204
 None
 1.50A 4yvpA-3lhxA:
undetectable		 4yvpA-3lhxA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 303
ALA A 335
GLY A 336
HIS A 361
ALA A 364
ILE A 368
 None
 0.50A 5kb6A-3lhxA:
31.4		 5kb6A-3lhxA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		6 / 12 GLY A 303
ALA A 335
GLY A 336
HIS A 361
ALA A 364
ILE A 368
 None
 0.47A 5kb6B-3lhxA:
31.6		 5kb6B-3lhxA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 159
TYR A 175
TYR A 162
ILE A 213
ALA A 181
 None
 1.16A 5kvaA-3lhxA:
3.6		 5kvaA-3lhxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3lhx KETODEOXYGLUCONOKINA
SE
(Shigella
flexneri) 		5 / 12 GLY A 159
TYR A 175
TYR A 162
ILE A 213
ALA A 181
 None
 1.14A 5kvaB-3lhxA:
3.5		 5kvaB-3lhxA:
19.88