SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3li9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		5 / 12 ALA A 255
GLY A 264
GLY A 265
PHE A  58
LEU A 230
 None
 0.99A 1ej0A-3li9A:
undetectable		 1ej0A-3li9A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		4 / 7 PRO A 284
SER A 291
ILE A 259
GLY A 265
 None
 0.91A 2y7kA-3li9A:
undetectable		 2y7kA-3li9A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		3 / 3 PRO A 134
PHE A 113
ALA A  87
 None
 0.65A 3itaD-3li9A:
2.3		 3itaD-3li9A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		4 / 4 GLY A 107
TYR A 105
GLY A 197
ASP A 183
 None
BTB  A   1 (-3.6A)
None
None
 1.13A 3kl3A-3li9A:
undetectable		 3kl3A-3li9A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		3 / 3 HIS A 126
ARG A  84
GLU A  85
 None
 0.97A 3qf1A-3li9A:
undetectable		 3qf1A-3li9A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		4 / 7 TYR A 157
ASP A 111
ALA A 112
ASP A 117
 None
 0.80A 3rodD-3li9A:
undetectable		 3rodD-3li9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		4 / 7 VAL A 285
THR A 287
LEU A 230
VAL A 180
 None
 1.04A 5e4dA-3li9A:
undetectable
5e4dB-3li9A:
undetectable		 5e4dA-3li9A:
23.21
5e4dB-3li9A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		3 / 3 ASN A  56
ASP A 289
GLY A 288
 None
 0.64A 5fctB-3li9A:
undetectable		 5fctB-3li9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		5 / 12 SER A 291
ILE A 259
ALA A  51
ILE A 212
ALA A 209
 None
 1.02A 5vceA-3li9A:
undetectable		 5vceA-3li9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		3 / 3 TYR A  79
ASP A 114
ASP A  83
 None
 0.79A 5x6yA-3li9A:
undetectable		 5x6yA-3li9A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		5 / 12 ALA A  69
LEU A 106
SER A  81
THR A  75
ALA A  77
 None
 1.18A 6djzC-3li9A:
undetectable		 6djzC-3li9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FU4_B_HSMB401_1
(PROBABLE CHEMOTAXIS
TRANSDUCER)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		5 / 9 TYR A 105
TYR A 135
GLU A 146
TYR A 172
ASP A 199
 BTB  A   1 (-3.6A)
BTB  A   1 (-4.1A)
None
BTB  A   1 (-4.6A)
BTB  A   1 (-2.9A)
 1.17A 6fu4B-3li9A:
27.1		 6fu4B-3li9A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FU4_D_HSMD401_1
(PROBABLE CHEMOTAXIS
TRANSDUCER)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		5 / 9 TYR A 105
TYR A 135
GLU A 146
TYR A 172
ASP A 199
 BTB  A   1 (-3.6A)
BTB  A   1 (-4.1A)
None
BTB  A   1 (-4.6A)
BTB  A   1 (-2.9A)
 1.14A 6fu4D-3li9A:
26.9		 6fu4D-3li9A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3li9 HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE
(Methanosarcina
mazei) 		3 / 3 TYR A 182
ASP A 166
GLN A  66
 None
 0.82A 6g1pA-3li9A:
undetectable		 6g1pA-3li9A:
22.47