SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_B_DVAB8_0 (GRAMICIDIN A)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	3 / 3	VAL A 283 VAL A 290 TRP A 288	None	0.96A	1av2A-3licA: undetectable 1av2B-3licA: undetectable	1av2A-3licA: 6.67 1av2B-3licA: 6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I9G_A_SAMA301_0 (HYPOTHETICAL PROTEIN RV2118C)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 12	ILE A 140 SER A 109 ARG A 130 ASP A 204 LEU A 179	None	1.06A	1i9gA-3licA: undetectable	1i9gA-3licA: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_B_NOVB444_1 (DNA GYRASE SUBUNIT B)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 12	ILE A 111 ASP A 139 ILE A 86 ALA A 81 THR A 197	None	1.21A	1kijB-3licA: undetectable	1kijB-3licA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_1 (SAM-DEPENDENT METHYLTRANSFERASE)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	4 / 4	GLY A 261 GLU A 282 ASP A 221 ASP A 260	None	1.28A	3mb5A-3licA: undetectable	3mb5A-3licA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RD0_A_EDPA175_1 (FERRITIN LIGHT CHAIN)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	4 / 6	SER A 125 TYR A 127 ALA A 112 LEU A 138	None EDO A 1 (-4.1A) None None	1.11A	3rd0A-3licA: undetectable	3rd0A-3licA: 23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTV_A_ADNA403_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 12	HIS A 65 SER A 109 ASP A 105 ASP A 200 ILE A 100	None None None EDO A 1 (-2.7A) None	1.45A	4ktvA-3licA: undetectable 4ktvB-3licA: undetectable	4ktvA-3licA: 22.84 4ktvB-3licA: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 12	PHE A 187 ILE A 86 VAL A 128 LEU A 92 LEU A 73	None	1.34A	4qzuA-3licA: undetectable	4qzuA-3licA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IH0_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	4 / 6	PHE A 106 PRO A 104 ARG A 205 ILE A 100	None	1.42A	5ih0A-3licA: undetectable	5ih0A-3licA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEA_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	4 / 5	LEU A 48 TYR A 276 LEU A 299 GLU A 298	None	1.01A	5weaA-3licA: undetectable	5weaA-3licA: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FU4_A_HSMA401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 9	TYR A 127 TRP A 154 TYR A 170 ASP A 172 ASP A 200	EDO A 1 (-4.1A) EDO A 1 (-3.4A) None EDO A 1 (-2.9A) EDO A 1 (-2.7A)	0.75A	6fu4A-3licA: 20.8	6fu4A-3licA: 13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FU4_B_HSMB401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 9	TYR A 127 TRP A 154 TYR A 170 ASP A 172 ASP A 200	EDO A 1 (-4.1A) EDO A 1 (-3.4A) None EDO A 1 (-2.9A) EDO A 1 (-2.7A)	0.73A	6fu4B-3licA: 18.8	6fu4B-3licA: 13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FU4_C_HSMC401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 9	TYR A 127 TRP A 154 TYR A 170 ASP A 172 ASP A 200	EDO A 1 (-4.1A) EDO A 1 (-3.4A) None EDO A 1 (-2.9A) EDO A 1 (-2.7A)	0.78A	6fu4C-3licA: 20.7	6fu4C-3licA: 13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FU4_D_HSMD401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	3lic	SENSOR PROTEIN (Shewanella oneidensis)	5 / 9	TYR A 127 TRP A 154 TYR A 170 ASP A 172 ASP A 200	EDO A 1 (-4.1A) EDO A 1 (-3.4A) None EDO A 1 (-2.9A) EDO A 1 (-2.7A)	0.77A	6fu4D-3licA: 20.3	6fu4D-3licA: 13.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_B_DVAB8_0","GRAMICIDIN A","3lic","SENSOR PROTEIN","Shewanella oneidensis",3,"VAL A 283;VAL A 290;TRP A 288","None","0.96A","1av2A-3licA:undetectable;1av2B-3licA:undetectable","1av2A-3licA:6.67;1av2B-3licA:6.67"],["1I9G_A_SAMA301_0","HYPOTHETICAL PROTEIN RV2118C","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"ILE A 140;SER A 109;ARG A 130;ASP A 204;LEU A 179","None","1.06A","1i9gA-3licA:undetectable","1i9gA-3licA:22.33"],["1KIJ_B_NOVB444_1","DNA GYRASE SUBUNIT B","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"ILE A 111;ASP A 139;ILE A  86;ALA A  81;THR A 197","None","1.21A","1kijB-3licA:undetectable","1kijB-3licA:21.18"],["3MB5_A_SAMA301_1","SAM-DEPENDENT METHYLTRANSFERASE","3lic","SENSOR PROTEIN","Shewanella oneidensis",4,"GLY A 261;GLU A 282;ASP A 221;ASP A 260","None","1.28A","3mb5A-3licA:undetectable","3mb5A-3licA:20.61"],["3RD0_A_EDPA175_1","FERRITIN LIGHT CHAIN","3lic","SENSOR PROTEIN","Shewanella oneidensis",4,"SER A 125;TYR A 127;ALA A 112;LEU A 138","None;EDO A   1 (-4.1A);None;None","1.11A","3rd0A-3licA:undetectable","3rd0A-3licA:23.36"],["4KTV_A_ADNA403_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2;S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"HIS A  65;SER A 109;ASP A 105;ASP A 200;ILE A 100","None;None;None;EDO A   1 (-2.7A);None","1.45A","4ktvA-3licA:undetectable;4ktvB-3licA:undetectable","4ktvA-3licA:22.84;4ktvB-3licA:22.84"],["4QZU_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"PHE A 187;ILE A  86;VAL A 128;LEU A  92;LEU A  73","None","1.34A","4qzuA-3licA:undetectable","4qzuA-3licA:19.92"],["5IH0_A_ACTA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","3lic","SENSOR PROTEIN","Shewanella oneidensis",4,"PHE A 106;PRO A 104;ARG A 205;ILE A 100","None","1.42A","5ih0A-3licA:undetectable","5ih0A-3licA:23.21"],["5WEA_A_IPHA901_0","PROTEIN ARGONAUTE-2","3lic","SENSOR PROTEIN","Shewanella oneidensis",4,"LEU A  48;TYR A 276;LEU A 299;GLU A 298","None","1.01A","5weaA-3licA:undetectable","5weaA-3licA:15.23"],["6FU4_A_HSMA401_1","PROBABLE CHEMOTAXIS TRANSDUCER","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"TYR A 127;TRP A 154;TYR A 170;ASP A 172;ASP A 200","EDO A   1 (-4.1A);EDO A   1 (-3.4A);None;EDO A   1 (-2.9A);EDO A   1 (-2.7A)","0.75A","6fu4A-3licA:20.8","6fu4A-3licA:13.87"],["6FU4_B_HSMB401_1","PROBABLE CHEMOTAXIS TRANSDUCER","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"TYR A 127;TRP A 154;TYR A 170;ASP A 172;ASP A 200","EDO A   1 (-4.1A);EDO A   1 (-3.4A);None;EDO A   1 (-2.9A);EDO A   1 (-2.7A)","0.73A","6fu4B-3licA:18.8","6fu4B-3licA:13.87"],["6FU4_C_HSMC401_1","PROBABLE CHEMOTAXIS TRANSDUCER","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"TYR A 127;TRP A 154;TYR A 170;ASP A 172;ASP A 200","EDO A   1 (-4.1A);EDO A   1 (-3.4A);None;EDO A   1 (-2.9A);EDO A   1 (-2.7A)","0.78A","6fu4C-3licA:20.7","6fu4C-3licA:13.87"],["6FU4_D_HSMD401_1","PROBABLE CHEMOTAXIS TRANSDUCER","3lic","SENSOR PROTEIN","Shewanella oneidensis",5,"TYR A 127;TRP A 154;TYR A 170;ASP A 172;ASP A 200","EDO A   1 (-4.1A);EDO A   1 (-3.4A);None;EDO A   1 (-2.9A);EDO A   1 (-2.7A)","0.77A","6fu4D-3licA:20.3","6fu4D-3licA:13.87"]]