SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3liz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	3liz	4C3 MONOCLONAL ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 123 PRO H 153 THR H 122 PRO H 124	None	1.34A	1dsdC-3lizH: undetectable	1dsdC-3lizH: 5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	3liz	4C3 MONOCLONAL ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 4	THR H 123 PRO H 153 THR H 122 PRO H 124	None	1.34A	1dsdC-3lizH: undetectable	1dsdC-3lizH: 5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_B_8MOB501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	3liz	4C3 MONOCLONAL ANTIBODY HEAVY CHAIN (Mus musculus)	6 / 11	PHE H 29 ASN H 74 GLY H 55 THR H 58 ILE H 70 LEU H 79	None	1.44A	1z11B-3lizH: undetectable	1z11B-3lizH: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	3liz	4C3 MONOCLONAL ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.75A	5ecmD-3lizH: undetectable	5ecmD-3lizH: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	3liz	4C3 MONOCLONAL ANTIBODY HEAVY CHAIN (Mus musculus)	4 / 7	ALA H 92 THR H 91 VAL H 115 GLU H 89	None	0.83A	5ecoD-3lizH: undetectable	5ecoD-3lizH: 20.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","3liz","4C3 MONOCLONAL ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 123;PRO H 153;THR H 122;PRO H 124","None","1.34A","1dsdC-3lizH:undetectable","1dsdC-3lizH:5.26"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","3liz","4C3 MONOCLONAL ANTIBODY HEAVY CHAIN","Mus musculus",4,"THR H 123;PRO H 153;THR H 122;PRO H 124","None","1.34A","1dsdC-3lizH:undetectable","1dsdC-3lizH:5.26"],["1Z11_B_8MOB501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","3liz","4C3 MONOCLONAL ANTIBODY HEAVY CHAIN","Mus musculus",6,"PHE H  29;ASN H  74;GLY H  55;THR H  58;ILE H  70;LEU H  79","None","1.44A","1z11B-3lizH:undetectable","1z11B-3lizH:18.64"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","3liz","4C3 MONOCLONAL ANTIBODY HEAVY CHAIN","Mus musculus",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.75A","5ecmD-3lizH:undetectable","5ecmD-3lizH:20.24"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","3liz","4C3 MONOCLONAL ANTIBODY HEAVY CHAIN","Mus musculus",4,"ALA H  92;THR H  91;VAL H 115;GLU H  89","None","0.83A","5ecoD-3lizH:undetectable","5ecoD-3lizH:20.24"]]