SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	3lj8	TYROSINE-PROTEIN PHOSPHATASE (Homo sapiens)	3 / 3	ASP A 259 PHE A 333 ARG A 296	None	0.82A	2a3aA-3lj8A: undetectable	2a3aA-3lj8A: 16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_B_CE3B302_2 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	3lj8	TYROSINE-PROTEIN PHOSPHATASE (Homo sapiens)	3 / 3	CYH A 290 PRO A 256 ASP A 259	None	0.98A	3hlwB-3lj8A: undetectable	3hlwB-3lj8A: 19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_B_ACTB901_0 (PYRANOSE 2-OXIDASE)	3lj8	TYROSINE-PROTEIN PHOSPHATASE (Homo sapiens)	4 / 6	SER A 266 GLN A 336 PHE A 269 PHE A 333	None	1.48A	3lskB-3lj8A: undetectable	3lskB-3lj8A: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_D_ACTD901_0 (PYRANOSE 2-OXIDASE)	3lj8	TYROSINE-PROTEIN PHOSPHATASE (Homo sapiens)	4 / 6	SER A 266 GLN A 336 PHE A 269 PHE A 333	None	1.47A	3lskD-3lj8A: undetectable	3lskD-3lj8A: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM5_A_CE3A301_2 (BETA-LACTAMASE CTX-M-14)	3lj8	TYROSINE-PROTEIN PHOSPHATASE (Homo sapiens)	3 / 3	CYH A 290 PRO A 256 ASP A 259	None	0.98A	4pm5A-3lj8A: undetectable	4pm5A-3lj8A: 19.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A3A_A_TEPA1436_1","CHITINASE","3lj8","TYROSINE-PROTEIN PHOSPHATASE","Homo sapiens",3,"ASP A 259;PHE A 333;ARG A 296","None","0.82A","2a3aA-3lj8A:undetectable","2a3aA-3lj8A:16.71"],["3HLW_B_CE3B302_2","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","3lj8","TYROSINE-PROTEIN PHOSPHATASE","Homo sapiens",3,"CYH A 290;PRO A 256;ASP A 259","None","0.98A","3hlwB-3lj8A:undetectable","3hlwB-3lj8A:19.69"],["3LSK_B_ACTB901_0","PYRANOSE 2-OXIDASE","3lj8","TYROSINE-PROTEIN PHOSPHATASE","Homo sapiens",4,"SER A 266;GLN A 336;PHE A 269;PHE A 333","None","1.48A","3lskB-3lj8A:undetectable","3lskB-3lj8A:15.16"],["3LSK_D_ACTD901_0","PYRANOSE 2-OXIDASE","3lj8","TYROSINE-PROTEIN PHOSPHATASE","Homo sapiens",4,"SER A 266;GLN A 336;PHE A 269;PHE A 333","None","1.47A","3lskD-3lj8A:undetectable","3lskD-3lj8A:15.16"],["4PM5_A_CE3A301_2","BETA-LACTAMASE CTX-M-14","3lj8","TYROSINE-PROTEIN PHOSPHATASE","Homo sapiens",3,"CYH A 290;PRO A 256;ASP A 259","None","0.98A","4pm5A-3lj8A:undetectable","4pm5A-3lj8A:19.69"]]