SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ljb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3ljb INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		3 / 3 THR A 416
GLU A 410
ASP A 478
 None
 0.74A 1nt2A-3ljbA:
undetectable		 1nt2A-3ljbA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3ljb INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		3 / 3 GLY A 397
GLU A 394
THR A 395
 None
 0.55A 4kouA-3ljbA:
undetectable		 4kouA-3ljbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ljb INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		3 / 3 TYR A 451
ARG A 452
THR A 456
 None
 0.77A 5z84J-3ljbA:
undetectable		 5z84J-3ljbA:
10.86