SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ljf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 9 GLY A  85
TYR A   9
ILE A  18
HIS A  17
GLY A 177
 None
 1.13A 1acjA-3ljfA:
undetectable		 1acjA-3ljfA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 CYH A  57
GLY A 149
LEU A 128
VAL A 126
ASP A 130
 None
 1.43A 1fpqA-3ljfA:
undetectable		 1fpqA-3ljfA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 SER A  79
TYR A   9
LEU A  14
GLY A 177
TYR A  76
 None
 1.20A 2b8jB-3ljfA:
undetectable		 2b8jB-3ljfA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 ILE A  11
TYR A  76
LEU A  80
GLU A  15
LEU A  14
 None
 1.31A 2bxfB-3ljfA:
undetectable		 2bxfB-3ljfA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 ILE A  18
LEU A 181
PHE A 178
TYR A 174
 None
 0.81A 2vdbA-3ljfA:
undetectable		 2vdbA-3ljfA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A 174
VAL A 156
ASP A 157
SER A 121
 None
None
FE  A5000 (-2.6A)
None
 1.22A 2x45A-3ljfA:
undetectable		 2x45A-3ljfA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 TYR A 174
VAL A 156
ASP A 157
SER A 121
 None
None
FE  A5000 (-2.6A)
None
 1.27A 2x45C-3ljfA:
undetectable		 2x45C-3ljfA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 VAL A 182
PHE A 178
ALA A 187
ILE A  96
PHE A 106
 None
 1.24A 3t3qA-3ljfA:
undetectable		 3t3qA-3ljfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 VAL A 182
PHE A 178
ALA A 187
ILE A  96
PHE A 106
 None
 1.26A 3t3qB-3ljfA:
undetectable		 3t3qB-3ljfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 VAL A 182
PHE A 178
ALA A 187
ILE A  96
PHE A 106
 None
 1.26A 3t3qC-3ljfA:
undetectable		 3t3qC-3ljfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 VAL A 182
PHE A 178
ALA A 187
ILE A  96
PHE A 106
 None
 1.30A 3t3qD-3ljfA:
undetectable		 3t3qD-3ljfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		4 / 6 TYR A 174
HIS A  26
HIS A  73
TYR A  76
 None
FE  A5000 (-3.3A)
FE  A5000 (-3.2A)
None
 1.49A 4df2A-3ljfA:
undetectable		 4df2A-3ljfA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 TYR A  76
SER A  79
TRP A  77
THR A  22
TYR A 174
 None
 1.49A 5dsgA-3ljfA:
undetectable		 5dsgA-3ljfA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 ILE A  18
LEU A 175
VAL A 156
LEU A  23
LEU A   7
 None
 0.82A 6b54A-3ljfA:
undetectable		 6b54A-3ljfA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 TRP A  77
LEU A  80
VAL A 156
THR A 123
ALA A 114
 None
 1.25A 6drxA-3ljfA:
undetectable		 6drxA-3ljfA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3ljf IRON SUPEROXIDE
DISMUTASE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 ASP A 130
ASP A 147
ASN A  72
 None
 0.85A 6gngB-3ljfA:
undetectable		 6gngB-3ljfA:
15.79