SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ljp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 LEU A 136
ALA A  27
ILE A 215
GLY A  94
VAL A 155
 None
 1.14A 1d4yA-3ljpA:
undetectable		 1d4yA-3ljpA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		3 / 3 GLN A 308
HIS A 506
PRO A 467
 None
 0.95A 1d8cA-3ljpA:
undetectable		 1d8cA-3ljpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 6 HIS A 257
ILE A 248
ALA A 261
VAL A  43
 None
 1.01A 1hk1A-3ljpA:
undetectable		 1hk1A-3ljpA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLU A 140
ASP A 141
PRO A 161
ILE A 199
ALA A 104
 None
 1.14A 1kijB-3ljpA:
undetectable		 1kijB-3ljpA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 PRO A 467
GLY A 313
ASN A 360
ASN A  82
ILE A  75
 None
 1.20A 1r30A-3ljpA:
undetectable		 1r30A-3ljpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 PRO A 467
GLY A 313
ASN A 360
ASN A  82
ILE A  75
 None
 1.19A 1r30B-3ljpA:
undetectable		 1r30B-3ljpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 6 ILE A  75
VAL A 401
VAL A 502
ILE A 518
 None
 0.74A 1uwhA-3ljpA:
undetectable		 1uwhA-3ljpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 7 PHE A 105
ASN A 185
ASN A 200
VAL A 160
 None
 1.36A 1wu8A-3ljpA:
undetectable
1wu8C-3ljpA:
undetectable		 1wu8A-3ljpA:
18.56
1wu8C-3ljpA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 8 ASP A  49
GLY A  21
GLU A  44
ILE A 215
 None
FDA  A 547 ( 4.7A)
FDA  A 547 (-2.7A)
None
 0.72A 2dtjA-3ljpA:
undetectable
2dtjB-3ljpA:
undetectable		 2dtjA-3ljpA:
18.26
2dtjB-3ljpA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		3 / 3 THR A 376
ASP A 309
SER A 384
 None
 0.86A 2nxeA-3ljpA:
3.4		 2nxeA-3ljpA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 LEU A 112
ASN A 125
MET A 473
VAL A 502
MET A 517
 None
 1.36A 2q7iA-3ljpA:
undetectable		 2q7iA-3ljpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 LEU A 112
ASN A 125
MET A 473
VAL A 502
MET A 517
 None
 1.35A 2q7kA-3ljpA:
undetectable		 2q7kA-3ljpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 LEU A 112
ASN A 125
MET A 473
VAL A 502
MET A 517
 None
 1.33A 2q7lA-3ljpA:
undetectable		 2q7lA-3ljpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 6 LEU A 226
ARG A  50
ILE A 215
ILE A 513
 None
 0.84A 2xkwB-3ljpA:
undetectable		 2xkwB-3ljpA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 HIS A 216
GLY A  21
SER A 209
SER A 268
LEU A  42
 None
FDA  A 547 ( 4.7A)
None
None
None
 1.19A 3cjtK-3ljpA:
undetectable		 3cjtK-3ljpA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 LEU A 136
ALA A  27
ILE A 215
GLY A  94
VAL A 155
 None
 0.94A 3em3B-3ljpA:
undetectable		 3em3B-3ljpA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 LEU A 226
THR A 225
ALA A  41
LEU A 259
LEU A   9
 None
 1.16A 3hm1A-3ljpA:
undetectable		 3hm1A-3ljpA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 4 PRO A 504
TYR A 119
GLY A 120
THR A 122
 None
 1.41A 3ib0A-3ljpA:
undetectable		 3ib0A-3ljpA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 LEU A 280
GLN A 234
LEU A 289
VAL A 303
THR A 269
 None
None
None
None
FDA  A 547 (-4.1A)
 1.14A 3ix9B-3ljpA:
undetectable		 3ix9B-3ljpA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A 469
ARG A 385
ASP A 499
VAL A  28
ILE A 518
 None
None
FDA  A 547 (-4.6A)
None
None
 1.24A 3k13A-3ljpA:
undetectable		 3k13A-3ljpA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A 469
ARG A 385
ASP A 499
VAL A  28
ILE A 518
 None
None
FDA  A 547 (-4.6A)
None
None
 1.22A 3k13B-3ljpA:
undetectable		 3k13B-3ljpA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A 469
ARG A 385
ASP A 499
VAL A  28
ILE A 518
 None
None
FDA  A 547 (-4.6A)
None
None
 1.23A 3k13C-3ljpA:
undetectable		 3k13C-3ljpA:
21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 5 ILE A 103
HIS A 351
HIS A 466
ASN A 510
 FDA  A 547 (-3.5A)
None
FDA  A 547 ( 4.6A)
FDA  A 547 (-4.6A)
 0.19A 3nneA-3ljpA:
67.5		 3nneA-3ljpA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NNE_B_ACTB601_0
(CHOLINE OXIDASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 5 TRP A  61
ILE A 103
HIS A 351
HIS A 466
 None
FDA  A 547 (-3.5A)
None
FDA  A 547 ( 4.6A)
 0.19A 3nneB-3ljpA:
67.9		 3nneB-3ljpA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NNE_D_ACTD601_0
(CHOLINE OXIDASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 5 TRP A  61
ILE A 103
TRP A 331
HIS A 351
 None
FDA  A 547 (-3.5A)
None
None
 0.15A 3nneD-3ljpA:
67.5		 3nneD-3ljpA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 6 ILE A 103
HIS A 351
HIS A 466
ASN A 510
 FDA  A 547 (-3.5A)
None
FDA  A 547 ( 4.6A)
FDA  A 547 (-4.6A)
 0.21A 3nneG-3ljpA:
67.6		 3nneG-3ljpA:
99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 GLY A 282
ASP A 299
GLY A 491
VAL A 471
VAL A 303
 None
 1.10A 3nu9B-3ljpA:
undetectable		 3nu9B-3ljpA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 ILE A 335
LEU A 348
GLY A 178
ALA A 177
THR A 337
 None
 1.00A 3uq6B-3ljpA:
3.2		 3uq6B-3ljpA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 8 VAL A  18
VAL A  40
ILE A 218
PHE A 224
 None
 0.75A 3warA-3ljpA:
undetectable		 3warA-3ljpA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 TYR A 465
TRP A  71
GLY A  95
GLU A  44
GLY A  46
 FDA  A 547 (-4.0A)
FDA  A 547 (-4.2A)
FDA  A 547 (-3.2A)
FDA  A 547 (-2.7A)
None
 1.41A 4ey7B-3ljpA:
undetectable		 4ey7B-3ljpA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A  25
GLY A  22
SER A 211
VAL A  18
VAL A  40
 None
FDA  A 547 (-3.1A)
None
None
None
 0.87A 4htfA-3ljpA:
2.7		 4htfA-3ljpA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A  25
GLY A  22
SER A 211
VAL A  18
VAL A  40
 None
FDA  A 547 (-3.1A)
None
None
None
 0.87A 4htfB-3ljpA:
undetectable		 4htfB-3ljpA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 GLY A  21
ALA A 498
VAL A  18
PHE A 224
ILE A 215
 FDA  A 547 ( 4.7A)
None
None
None
None
 1.40A 4j4vA-3ljpA:
0.5		 4j4vA-3ljpA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 GLY A  21
ALA A 498
VAL A  18
PHE A 224
ILE A 215
 FDA  A 547 ( 4.7A)
None
None
None
None
 1.34A 4j4vD-3ljpA:
undetectable
4j4vE-3ljpA:
0.5		 4j4vD-3ljpA:
18.84
4j4vE-3ljpA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		3 / 3 LEU A 132
MET A 517
ASP A  35
 None
 0.80A 4j7xB-3ljpA:
3.1		 4j7xB-3ljpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A  43
ALA A  45
TRP A  71
LEU A 235
VAL A  19
 None
FDA  A 547 (-3.6A)
FDA  A 547 (-4.2A)
None
None
 1.24A 4kyaB-3ljpA:
undetectable		 4kyaB-3ljpA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A  43
ALA A  45
TRP A  71
LEU A 235
VAL A  19
 None
FDA  A 547 (-3.6A)
FDA  A 547 (-4.2A)
None
None
 1.23A 4kyaD-3ljpA:
undetectable		 4kyaD-3ljpA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A  43
ALA A  45
TRP A  71
LEU A 235
VAL A  19
 None
FDA  A 547 (-3.6A)
FDA  A 547 (-4.2A)
None
None
 1.24A 4kyaF-3ljpA:
undetectable		 4kyaF-3ljpA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A  43
ALA A  45
TRP A  71
LEU A 235
VAL A  19
 None
FDA  A 547 (-3.6A)
FDA  A 547 (-4.2A)
None
None
 1.21A 4kyaH-3ljpA:
undetectable		 4kyaH-3ljpA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		3 / 3 TRP A 436
GLN A 430
THR A 437
 None
 0.78A 4m2xA-3ljpA:
undetectable		 4m2xA-3ljpA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		4 / 8 SER A 501
VAL A 471
VAL A  19
GLY A  20
 None
None
None
FDA  A 547 (-3.2A)
 0.76A 4mk4A-3ljpA:
undetectable		 4mk4A-3ljpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A 502
ALA A 500
VAL A 515
SER A 268
GLY A 270
 None
FDA  A 547 (-3.3A)
FDA  A 547 (-4.7A)
None
FDA  A 547 (-3.6A)
 1.30A 4mm4B-3ljpA:
undetectable		 4mm4B-3ljpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 9 ALA A 447
TYR A 456
GLY A 365
SER A 442
GLY A 444
 None
 1.29A 4mmeA-3ljpA:
undetectable		 4mmeA-3ljpA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A  25
GLY A  21
SER A 211
MET A  93
ALA A  29
 None
FDA  A 547 ( 4.7A)
None
None
None
 1.03A 4qtuB-3ljpA:
undetectable		 4qtuB-3ljpA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A 497
LEU A  42
VAL A  28
GLY A  25
ALA A  24
 None
None
None
None
FDA  A 547 (-3.8A)
 1.11A 4rrxA-3ljpA:
undetectable		 4rrxA-3ljpA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 VAL A 497
LEU A  42
VAL A  28
GLY A  25
ALA A  24
 None
None
None
None
FDA  A 547 (-3.8A)
 1.11A 4rrxB-3ljpA:
undetectable		 4rrxB-3ljpA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 SER A 210
GLY A  95
GLY A  94
MET A 516
ASP A  49
 None
FDA  A 547 (-3.2A)
None
None
None
 1.28A 4ubeA-3ljpA:
4.0		 4ubeA-3ljpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 GLY A 353
GLU A 332
THR A 166
VAL A 355
SER A 327
 None
 0.98A 4yb6A-3ljpA:
undetectable
4yb6E-3ljpA:
undetectable		 4yb6A-3ljpA:
20.55
4yb6E-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 GLY A 353
GLU A 332
THR A 166
VAL A 355
SER A 327
 None
 0.97A 4yb6B-3ljpA:
undetectable
4yb6C-3ljpA:
undetectable		 4yb6B-3ljpA:
20.55
4yb6C-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 GLY A 353
GLU A 332
THR A 166
VAL A 355
SER A 327
 None
 0.98A 4yb6C-3ljpA:
undetectable
4yb6F-3ljpA:
undetectable		 4yb6C-3ljpA:
20.55
4yb6F-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 SER A 327
GLY A 353
GLU A 332
THR A 166
VAL A 355
 None
 0.96A 4yb6A-3ljpA:
undetectable
4yb6D-3ljpA:
undetectable		 4yb6A-3ljpA:
20.55
4yb6D-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 SER A 327
GLY A 353
GLU A 332
THR A 166
VAL A 355
 None
 0.96A 4yb6D-3ljpA:
undetectable
4yb6E-3ljpA:
undetectable		 4yb6D-3ljpA:
20.55
4yb6E-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 SER A 327
GLY A 353
GLU A 332
THR A 166
VAL A 355
 None
 0.99A 4yb6B-3ljpA:
undetectable
4yb6F-3ljpA:
undetectable		 4yb6B-3ljpA:
20.55
4yb6F-3ljpA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 12 GLY A 469
GLY A 270
ASP A 273
GLY A 386
HIS A  87
 None
FDA  A 547 (-3.6A)
FDA  A 547 (-3.4A)
None
None
 1.16A 5hikA-3ljpA:
undetectable		 5hikA-3ljpA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		3 / 3 THR A 508
HIS A 310
ASN A 510
 None
None
FDA  A 547 (-4.6A)
 0.85A 5n4tA-3ljpA:
undetectable		 5n4tA-3ljpA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 VAL A  19
GLY A  20
GLU A  44
ALA A 232
LEU A 277
 None
FDA  A 547 (-3.2A)
FDA  A 547 (-2.7A)
FDA  A 547 (-3.6A)
None
 0.79A 5x6yA-3ljpA:
undetectable		 5x6yA-3ljpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 10 VAL A  19
GLY A  20
GLU A  44
ALA A 232
LEU A 277
 None
FDA  A 547 (-3.2A)
FDA  A 547 (-2.7A)
FDA  A 547 (-3.6A)
None
 0.68A 5x6yB-3ljpA:
undetectable		 5x6yB-3ljpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 VAL A  19
GLY A  20
GLU A  44
ALA A 232
LEU A 277
 None
FDA  A 547 (-3.2A)
FDA  A 547 (-2.7A)
FDA  A 547 (-3.6A)
None
 0.75A 5x6yC-3ljpA:
undetectable		 5x6yC-3ljpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3ljp CHOLINE OXIDASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 506
VAL A 416
HIS A 381
ASP A 347
PRO A 346
 None
 1.34A 5z0fA-3ljpA:
undetectable
5z0fB-3ljpA:
undetectable		 5z0fA-3ljpA:
9.23
5z0fB-3ljpA:
9.94