SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 ARG A 191
ASP A 172
SER A 218
ASN A 170
 PEG  A 645 ( 3.5A)
None
None
None
 1.43A 1kiaB-3lk6A:
3.6		 1kiaB-3lk6A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 6 ARG A 191
ASP A 172
SER A 218
ASN A 170
 PEG  A 645 ( 3.5A)
None
None
None
 1.44A 1kiaC-3lk6A:
3.4		 1kiaC-3lk6A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 ALA A 346
VAL A 339
ALA A 338
HIS A 270
 None
 1.05A 1q23A-3lk6A:
undetectable		 1q23A-3lk6A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 ALA A 346
VAL A 339
ALA A 338
HIS A 270
 None
 1.15A 1q23F-3lk6A:
undetectable		 1q23F-3lk6A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 ALA A 346
VAL A 339
ALA A 338
HIS A 270
 None
 1.10A 1q23K-3lk6A:
undetectable		 1q23K-3lk6A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 PHE A 447
ILE A 472
ILE A 511
VAL A 558
ILE A 468
 None
 1.20A 1r5lA-3lk6A:
undetectable		 1r5lA-3lk6A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 ALA A 219
ASP A 264
VAL A 314
ILE A  90
 None
 0.73A 1t7iB-3lk6A:
undetectable		 1t7iB-3lk6A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 ALA A 219
ASP A 264
VAL A 314
ILE A  90
 None
 0.71A 1t7jB-3lk6A:
undetectable		 1t7jB-3lk6A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 PHE A 571
PRO A 521
THR A 621
VAL A 620
ILE A 617
 None
 1.19A 2o7oA-3lk6A:
0.5		 2o7oA-3lk6A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ALA A 294
GLY A 303
THR A 317
VAL A 343
PRO A 293
 None
 1.13A 2okcA-3lk6A:
undetectable		 2okcA-3lk6A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA802_0
(FERROCHELATASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 6 MET A 322
ARG A 191
PRO A 293
VAL A 271
 None
PEG  A 645 ( 3.5A)
None
None
 1.45A 2qd4A-3lk6A:
2.2		 2qd4A-3lk6A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 ILE A 511
GLN A 464
LEU A 562
LEU A 559
 None
 1.03A 2qqcB-3lk6A:
undetectable
2qqcC-3lk6A:
undetectable		 2qqcB-3lk6A:
11.24
2qqcC-3lk6A:
5.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 LEU A 562
LEU A 559
ILE A 511
GLN A 464
 None
 1.00A 2qqcA-3lk6A:
undetectable
2qqcF-3lk6A:
undetectable		 2qqcA-3lk6A:
5.84
2qqcF-3lk6A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 LEU A 562
LEU A 559
ILE A 511
GLN A 464
 None
 1.02A 2qqcG-3lk6A:
undetectable
2qqcJ-3lk6A:
undetectable		 2qqcG-3lk6A:
5.84
2qqcJ-3lk6A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 LEU A 562
LEU A 559
ILE A 511
GLN A 464
 None
 1.00A 2qqcI-3lk6A:
undetectable
2qqcL-3lk6A:
undetectable		 2qqcI-3lk6A:
5.84
2qqcL-3lk6A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 PHE A 571
PRO A 521
THR A 621
VAL A 620
ILE A 617
 None
 1.12A 2tctA-3lk6A:
0.8		 2tctA-3lk6A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 ASP A 107
ILE A 116
LEU A 167
THR A 106
ILE A  38
 NA  A 647 (-3.2A)
None
None
NA  A 647 (-3.9A)
None
 1.24A 2v0mA-3lk6A:
undetectable		 2v0mA-3lk6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 GLU A 427
ALA A 147
PRO A 139
ALA A 143
 None
 1.12A 2zgwA-3lk6A:
undetectable		 2zgwA-3lk6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 6 ALA A 431
ASN A 595
PRO A 597
ALA A 598
 None
 1.17A 2zgwB-3lk6A:
undetectable		 2zgwB-3lk6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 6 GLU A 427
ALA A 147
PRO A 139
ALA A 143
 None
 1.08A 2zgwB-3lk6A:
undetectable		 2zgwB-3lk6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ALA A 568
VAL A 580
PRO A 614
VAL A 615
ILE A 617
 None
 0.93A 3cyxA-3lk6A:
undetectable		 3cyxA-3lk6A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ILE A 596
GLY A 599
ALA A 607
ALA A 579
VAL A 580
 None
 1.05A 3jb3A-3lk6A:
undetectable		 3jb3A-3lk6A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 LEU A 132
LEU A 164
SER A 158
ASP A 172
 None
 1.01A 3lm8A-3lk6A:
2.1
3lm8C-3lk6A:
undetectable		 3lm8A-3lk6A:
15.88
3lm8C-3lk6A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 ASP A  55
ASN A  95
SER A 351
 None
 0.85A 3lslA-3lk6A:
undetectable
3lslD-3lk6A:
1.4		 3lslA-3lk6A:
18.94
3lslD-3lk6A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 SER A 351
ASP A  55
ASN A  95
 None
 0.82A 3lslA-3lk6A:
undetectable
3lslD-3lk6A:
1.5		 3lslA-3lk6A:
18.94
3lslD-3lk6A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 VAL A 437
ILE A 636
GLY A 605
VAL A 580
ILE A 578
 None
 0.99A 3nu6A-3lk6A:
undetectable		 3nu6A-3lk6A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 8 ALA A 219
ASP A 264
VAL A 314
ILE A  90
 None
 0.76A 3nu9A-3lk6A:
undetectable		 3nu9A-3lk6A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 VAL A 335
ILE A 377
MET A  42
ARG A 363
 None
 1.37A 3oezA-3lk6A:
undetectable		 3oezA-3lk6A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 ALA A 568
VAL A 580
PRO A 614
VAL A 615
ILE A 617
 None
 0.95A 3oxvB-3lk6A:
undetectable		 3oxvB-3lk6A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 ALA A 568
VAL A 580
PRO A 614
VAL A 615
ILE A 617
 None
 0.96A 3oxvD-3lk6A:
undetectable		 3oxvD-3lk6A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ALA A 568
VAL A 580
PRO A 614
VAL A 615
ILE A 617
 None
 0.95A 3oxxC-3lk6A:
undetectable		 3oxxC-3lk6A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 VAL A 335
ILE A 377
MET A  42
ARG A 363
 None
 1.49A 3pyyB-3lk6A:
undetectable		 3pyyB-3lk6A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 THR A 171
GLY A 397
ILE A 216
ASN A 170
PRO A 117
 None
 1.07A 3q87B-3lk6A:
undetectable		 3q87B-3lk6A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 GLY A 133
GLY A 419
GLN A 124
LYS A 416
ALA A 414
 None
 1.24A 3qowA-3lk6A:
undetectable		 3qowA-3lk6A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 VAL A 271
VAL A 187
LEU A 291
ASP A 230
 None
PEG  A 645 ( 4.2A)
None
None
 0.89A 3rgfA-3lk6A:
undetectable		 3rgfA-3lk6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 7 ILE A 160
GLY A 157
PHE A 193
LEU A 144
 None
 0.82A 3v7pA-3lk6A:
undetectable		 3v7pA-3lk6A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 LYS A 451
LYS A 482
PRO A 483
 None
PEG  A 643 (-2.6A)
None
 1.24A 4dv1L-3lk6A:
undetectable		 4dv1L-3lk6A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 VAL A 558
GLY A 599
SER A 561
SER A 514
GLY A 513
 None
 1.16A 4mmdB-3lk6A:
undetectable		 4mmdB-3lk6A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 LEU A 559
ALA A 579
ASN A 595
ILE A 603
ILE A 468
 None
 1.01A 4o2bB-3lk6A:
6.4		 4o2bB-3lk6A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 LEU A 220
GLN A 256
LEU A 304
MET A 309
THR A 268
 None
 1.14A 4olmA-3lk6A:
undetectable		 4olmA-3lk6A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 THR A 200
GLY A 227
ASP A 228
SER A 192
 None
 1.24A 4rfqA-3lk6A:
undetectable		 4rfqA-3lk6A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 VAL A  81
TYR A 109
ALA A 112
 None
 0.52A 4ybnA-3lk6A:
undetectable		 4ybnA-3lk6A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 LEU A  52
ILE A 345
GLY A  49
ILE A 389
 None
 0.81A 5dzk3-3lk6A:
undetectable
5dzkm-3lk6A:
undetectable		 5dzk3-3lk6A:
0.32
5dzkm-3lk6A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 ILE A 345
GLY A  49
ILE A 389
LEU A  52
 None
 0.78A 5dzkB-3lk6A:
undetectable
5dzkI-3lk6A:
undetectable
5dzkW-3lk6A:
undetectable		 5dzkB-3lk6A:
16.40
5dzkI-3lk6A:
16.31
5dzkW-3lk6A:
0.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 ILE A 345
GLY A  49
ILE A 389
LEU A  52
 None
 0.79A 5dzki-3lk6A:
undetectable
5dzkj-3lk6A:
undetectable
5dzkx-3lk6A:
undetectable		 5dzki-3lk6A:
16.31
5dzkj-3lk6A:
16.31
5dzkx-3lk6A:
0.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 4 ILE A 345
GLY A  49
ILE A 389
LEU A  52
 None
 0.69A 5dzkl-3lk6A:
undetectable
5dzkz-3lk6A:
undetectable		 5dzkl-3lk6A:
16.31
5dzkz-3lk6A:
0.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 9 ALA A 263
GLN A 212
PRO A 254
ILE A 259
PHE A 255
 None
 1.39A 5i73A-3lk6A:
2.0		 5i73A-3lk6A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 5 ILE A 179
LEU A 144
GLY A 145
PHE A 193
 None
 0.90A 5kmdC-3lk6A:
3.2
5kmdD-3lk6A:
2.3		 5kmdC-3lk6A:
18.61
5kmdD-3lk6A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ASP A 123
PHE A 173
ARG A 191
LYS A 221
HIS A 222
 None
None
PEG  A 645 ( 3.5A)
None
PEG  A 645 (-3.3A)
 1.18A 5m6gA-3lk6A:
33.5		 5m6gA-3lk6A:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ASP A 123
PHE A 173
LYS A 221
HIS A 222
MET A 267
 None
None
None
PEG  A 645 (-3.3A)
None
 0.73A 5m6gA-3lk6A:
33.5		 5m6gA-3lk6A:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 SER A 174
SER A 218
PHE A 193
 None
 0.68A 5mugA-3lk6A:
undetectable		 5mugA-3lk6A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 PHE A 604
ILE A 472
ILE A 457
ALA A 459
GLU A 432
 None
 1.03A 5vceA-3lk6A:
undetectable		 5vceA-3lk6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 12 ASN A 196
LEU A 630
GLY A 145
ALA A 146
LEU A 642
 None
 1.47A 5x23A-3lk6A:
undetectable		 5x23A-3lk6A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 PHE A 276
ASP A 277
LYS A 299
 None
 0.82A 6awtD-3lk6A:
undetectable		 6awtD-3lk6A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 VAL A 437
ILE A 636
GLY A 605
VAL A 580
ILE A 578
 None
 0.98A 6dj2A-3lk6A:
undetectable		 6dj2A-3lk6A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.86A 6ebpB-3lk6A:
undetectable		 6ebpB-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.86A 6ebpC-3lk6A:
undetectable		 6ebpC-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 455
 None
 1.08A 6ebpD-3lk6A:
undetectable		 6ebpD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 10 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.87A 6ebpD-3lk6A:
undetectable		 6ebpD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 455
 None
 1.07A 6ebzA-3lk6A:
undetectable		 6ebzA-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.85A 6ebzA-3lk6A:
undetectable		 6ebzA-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.88A 6ebzB-3lk6A:
undetectable		 6ebzB-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.87A 6ebzC-3lk6A:
undetectable		 6ebzC-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 455
 None
 1.07A 6ebzD-3lk6A:
undetectable		 6ebzD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.87A 6ebzD-3lk6A:
undetectable		 6ebzD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		3 / 3 HIS A 222
ARG A 191
ILE A 188
 PEG  A 645 (-3.3A)
PEG  A 645 ( 3.5A)
PEG  A 645 ( 4.8A)
 0.81A 6fgdA-3lk6A:
5.2		 6fgdA-3lk6A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.88A 6gp2A-3lk6A:
undetectable		 6gp2A-3lk6A:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		5 / 11 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
 None
 0.94A 6gp2B-3lk6A:
undetectable		 6gp2B-3lk6A:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3lk6 LIPOPROTEIN YBBD
(Bacillus
subtilis) 		4 / 8 TYR A 515
VAL A 517
ASN A 564
GLN A 593
 None
 0.85A 6hzpA-3lk6A:
2.1		 6hzpA-3lk6A:
21.23