SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 3lkj CD40 LIGAND
(Homo
sapiens) 		3 / 3 VAL A 239
VAL A 237
TRP A 140
 None
 0.65A 1av2C-3lkjA:
undetectable
1av2D-3lkjA:
undetectable		 1av2C-3lkjA:
4.96
1av2D-3lkjA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 3lkj CD40 LIGAND
(Homo
sapiens) 		3 / 3 VAL A 239
VAL A 237
TRP A 140
 None
 0.64A 1w5uC-3lkjA:
undetectable
1w5uD-3lkjA:
undetectable		 1w5uC-3lkjA:
4.96
1w5uD-3lkjA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 3lkj CD40 LIGAND
(Homo
sapiens) 		3 / 3 VAL A 237
TRP A 140
VAL A 239
 None
 0.50A 2izqA-3lkjA:
undetectable
2izqB-3lkjA:
undetectable		 2izqA-3lkjA:
4.96
2izqB-3lkjA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3lkj CD40 LIGAND
(Homo
sapiens) 		3 / 3 VAL A 239
VAL A 237
TRP A 140
 None
 0.45A 3l8lA-3lkjA:
undetectable
3l8lB-3lkjA:
undetectable		 3l8lA-3lkjA:
4.96
3l8lB-3lkjA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 3lkj CD40 LIGAND
(Homo
sapiens) 		3 / 3 VAL A 239
VAL A 237
TRP A 140
 None
 0.60A 3l8lC-3lkjA:
undetectable
3l8lD-3lkjA:
undetectable		 3l8lC-3lkjA:
4.96
3l8lD-3lkjA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3lkj CD40 LIGAND
(Homo
sapiens) 		4 / 5 GLN A 160
THR A 254
HIS A 249
GLY A 158
 None
 1.10A 6gbnC-3lkjA:
undetectable		 6gbnC-3lkjA:
15.31