SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 3lkl ANTISIGMA-FACTOR
ANTAGONIST STAS
(Rhodobacter
sphaeroides) 		3 / 3 PHE A   1
SER A  57
LEU A  61
 None
 0.81A 2w1bA-3lklA:
undetectable		 2w1bA-3lklA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3lkl ANTISIGMA-FACTOR
ANTAGONIST STAS
(Rhodobacter
sphaeroides) 		4 / 8 PHE A  36
ILE A  45
ALA A  60
VAL A  18
 None
 0.91A 3me6B-3lklA:
undetectable		 3me6B-3lklA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3lkl ANTISIGMA-FACTOR
ANTAGONIST STAS
(Rhodobacter
sphaeroides) 		4 / 7 PHE A  34
VAL A  18
ILE A  45
SER A  57
 None
 0.96A 3pglA-3lklA:
undetectable		 3pglA-3lklA:
20.21