SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lkv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		4 / 7 GLN A  34
ILE A  95
TYR A  67
PHE A  65
 None
 1.10A 1e71M-3lkvA:
undetectable		 1e71M-3lkvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		4 / 7 GLN A  34
ILE A  95
TYR A  67
PHE A  65
 None
 1.13A 1e72M-3lkvA:
undetectable		 1e72M-3lkvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		4 / 6 GLN A  34
ILE A  95
TYR A  67
PHE A  65
 None
 1.10A 1e73M-3lkvA:
undetectable		 1e73M-3lkvA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 VAL A 164
GLY A 163
LEU A 191
LEU A 182
SER A 183
 None
 1.06A 1fduA-3lkvA:
6.0		 1fduA-3lkvA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		4 / 7 GLY A 266
ALA A 116
THR A 269
ILE A 265
 None
PHE  A 601 (-4.6A)
None
None
 0.81A 1gtnA-3lkvA:
undetectable
1gtnK-3lkvA:
undetectable		 1gtnA-3lkvA:
13.76
1gtnK-3lkvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		4 / 8 GLY A 266
ALA A 116
THR A 269
ILE A 265
 None
PHE  A 601 (-4.6A)
None
None
 0.82A 1gtnP-3lkvA:
undetectable
1gtnQ-3lkvA:
undetectable		 1gtnP-3lkvA:
13.76
1gtnQ-3lkvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A  94
VAL A 117
ALA A  31
GLY A 138
LEU A 277
 None
PHE  A 601 (-3.7A)
None
None
None
 1.08A 1kiaC-3lkvA:
undetectable		 1kiaC-3lkvA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A  94
VAL A 117
ALA A  31
GLY A 138
LEU A 277
 None
PHE  A 601 (-3.7A)
None
None
None
 1.09A 1nbhB-3lkvA:
undetectable		 1nbhB-3lkvA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A 162
GLY A 163
ALA A 194
ALA A 210
PRO A 241
 None
 0.99A 3jayA-3lkvA:
undetectable		 3jayA-3lkvA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A 162
GLY A 163
ALA A 194
ALA A 210
PRO A 241
 None
 0.88A 3jb2A-3lkvA:
undetectable		 3jb2A-3lkvA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 176
GLY A 259
THR A 247
SER A 248
LEU A 219
 None
 1.39A 3okxA-3lkvA:
undetectable		 3okxA-3lkvA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A 220
ALA A 218
LEU A 219
ILE A 255
GLY A 253
 PHE  A 601 (-4.0A)
None
None
None
None
 0.97A 3ozwB-3lkvA:
3.8		 3ozwB-3lkvA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 8 TYR A 217
ILE A 152
LYS A 153
ILE A 162
ALA A 184
 None
 1.21A 4ou1A-3lkvA:
2.2		 4ou1A-3lkvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 9 THR A  69
ALA A  77
THR A  99
ALA A 102
GLY A  72
 None
 1.23A 4qvnY-3lkvA:
undetectable
4qvnZ-3lkvA:
undetectable		 4qvnY-3lkvA:
22.26
4qvnZ-3lkvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A  43
ALA A 245
GLY A 259
GLU A 251
TYR A 249
 None
 0.88A 4r29C-3lkvA:
undetectable		 4r29C-3lkvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A  43
ALA A 245
GLY A 259
GLU A 251
TYR A 249
 None
 0.90A 4r29D-3lkvA:
undetectable		 4r29D-3lkvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 11 TYR A 272
VAL A 113
GLY A  94
ALA A  77
VAL A 117
 None
None
None
None
PHE  A 601 (-3.7A)
 1.17A 6hu9A-3lkvA:
undetectable
6hu9E-3lkvA:
undetectable
6hu9I-3lkvA:
undetectable		 6hu9A-3lkvA:
23.83
6hu9E-3lkvA:
21.74
6hu9I-3lkvA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3lkv UNCHARACTERIZED
CONSERVED DOMAIN
PROTEIN
(Vibrio
cholerae) 		5 / 10 TYR A 272
VAL A 113
GLY A  94
ALA A  77
VAL A 117
 None
None
None
None
PHE  A 601 (-3.7A)
 1.19A 6hu9L-3lkvA:
undetectable
6hu9P-3lkvA:
undetectable
6hu9T-3lkvA:
undetectable		 6hu9L-3lkvA:
23.83
6hu9P-3lkvA:
21.74
6hu9T-3lkvA:
13.88