SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ll7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.04A 1c8lA-3ll7A:
undetectable
1c8lA-3ll7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.00A 1gfzA-3ll7A:
3.0
1gfzA-3ll7A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.07A 1l5qA-3ll7A:
undetectable
1l5qA-3ll7A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.09A 1l5qB-3ll7A:
3.9
1l5qB-3ll7A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.07A 1l7xA-3ll7A:
undetectable
1l7xA-3ll7A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.11A 1l7xB-3ll7A:
undetectable
1l7xB-3ll7A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 ILE A 279
GLU A 276
PHE A 269
ALA A 303
None
1.16A 1oniD-3ll7A:
undetectable
1oniE-3ll7A:
undetectable
1oniD-3ll7A:
16.63
1oniE-3ll7A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 ILE A 279
GLU A 276
PHE A 269
ALA A 303
None
1.10A 1oniG-3ll7A:
undetectable
1oniI-3ll7A:
undetectable
1oniG-3ll7A:
16.63
1oniI-3ll7A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 ARG A 171
TYR A 165
ASP A 104
GLU A 185
None
None
FMT  A 503 (-4.0A)
None
1.14A 1rjdA-3ll7A:
7.5
1rjdA-3ll7A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 4 LEU A  47
ILE A  33
ARG A  38
TYR A  65
None
1.42A 1rk3A-3ll7A:
undetectable
1rk3A-3ll7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 SER A  85
ALA A 107
SER A 110
SER A  82
None
1.06A 2i91A-3ll7A:
undetectable
2i91A-3ll7A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 SER A  85
ALA A 107
SER A 110
SER A  82
None
1.06A 2i91B-3ll7A:
undetectable
2i91B-3ll7A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 5 LEU A  47
ILE A  33
ARG A  38
TYR A  65
None
1.42A 2zlcA-3ll7A:
undetectable
2zlcA-3ll7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.06A 3dd1A-3ll7A:
undetectable
3dd1A-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.05A 3dd1B-3ll7A:
undetectable
3dd1B-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.07A 3ddsA-3ll7A:
undetectable
3ddsA-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.07A 3ddsB-3ll7A:
undetectable
3ddsB-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.04A 3ddwA-3ll7A:
undetectable
3ddwA-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 269
HIS A 295
ALA A 301
GLY A 302
None
FMT  A 504 ( 4.1A)
None
None
1.08A 3ddwB-3ll7A:
undetectable
3ddwB-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 4 LEU A 219
ALA A 204
VAL A 166
PRO A 168
None
1.20A 3gv1B-3ll7A:
undetectable
3gv1B-3ll7A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
3 / 3 ARG A  86
GLU A 224
TYR A 163
None
0.94A 3k37B-3ll7A:
undetectable
3k37B-3ll7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 4 GLY A  99
GLU A 119
ASP A 148
ASP A 167
None
None
None
EDO  A 507 (-4.1A)
1.25A 3mb5A-3ll7A:
13.1
3mb5A-3ll7A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 ASP A  96
GLY A 102
LEU A 108
TYR A 165
None
FMT  A 503 (-3.8A)
None
None
1.11A 3w9tB-3ll7A:
undetectable
3w9tB-3ll7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 5 ASP A  96
GLY A 102
TYR A 165
ASP A 167
None
FMT  A 503 (-3.8A)
None
EDO  A 507 (-4.1A)
1.41A 3w9tD-3ll7A:
undetectable
3w9tD-3ll7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 ASP A  96
GLY A 102
LEU A 108
TYR A 165
None
FMT  A 503 (-3.8A)
None
None
1.11A 3w9tE-3ll7A:
undetectable
3w9tE-3ll7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 ASP A  96
GLY A 102
LEU A 108
TYR A 165
None
FMT  A 503 (-3.8A)
None
None
1.10A 3w9tF-3ll7A:
undetectable
3w9tF-3ll7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 PHE A 345
ILE A 343
PRO A 344
PHE A 367
None
1.20A 4fgkA-3ll7A:
2.1
4fgkA-3ll7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
3 / 3 LYS A 386
LEU A 402
ALA A 360
None
0.73A 4ikiA-3ll7A:
undetectable
4ikiA-3ll7A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
3 / 3 LYS A 315
ILE A 281
ILE A 279
None
0.69A 4y0qA-3ll7A:
undetectable
4y0qA-3ll7A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 LYS A 315
TYR A 323
GLY A 302
ASP A 211
None
1.22A 5emlA-3ll7A:
6.6
5emlA-3ll7A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 GLY A 100
GLU A 119
ASP A 148
ASP A 167
EDO  A 507 ( 3.8A)
None
None
EDO  A 507 (-4.1A)
0.65A 5ergB-3ll7A:
11.5
5ergB-3ll7A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 7 THR A 392
PHE A 345
LEU A 369
SER A 378
FMT  A 510 ( 3.9A)
None
None
None
1.30A 5uxcA-3ll7A:
undetectable
5uxcA-3ll7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 GLU A 119
ARG A 120
ASP A 148
ASP A 167
None
None
None
EDO  A 507 (-4.1A)
1.00A 5zw4A-3ll7A:
12.6
5zw4A-3ll7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 VAL A 399
LEU A 322
LEU A 316
HIS A 317
None
None
None
FMT  A 510 (-4.1A)
1.02A 6e43A-3ll7A:
undetectable
6e43A-3ll7A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 VAL A 399
LEU A 322
LEU A 316
HIS A 317
None
None
None
FMT  A 510 (-4.1A)
1.03A 6e43B-3ll7A:
undetectable
6e43B-3ll7A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis)
4 / 6 VAL A 399
LEU A 322
LEU A 316
HIS A 317
None
None
None
FMT  A 510 (-4.1A)
1.01A 6e43C-3ll7A:
undetectable
6e43C-3ll7A:
23.33