SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3llc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 12 GLY A 115
GLY A  43
ILE A 142
ALA A 119
LEU A 120
 None
 1.18A 1jg2A-3llcA:
undetectable		 1jg2A-3llcA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 5 ARG A  29
LEU A  55
ASP A  58
LEU A  27
 None
EDO  A 275 ( 4.2A)
None
None
 1.22A 1n13B-3llcA:
undetectable
1n13C-3llcA:
undetectable		 1n13B-3llcA:
17.78
1n13C-3llcA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		3 / 3 ARG A  22
ASP A 100
ASN A 132
 None
None
EDO  A 273 (-4.1A)
 0.94A 1nbhA-3llcA:
2.0		 1nbhA-3llcA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		3 / 3 ARG A  22
ASP A 100
ASN A 132
 None
None
EDO  A 273 (-4.1A)
 0.95A 1nbhD-3llcA:
undetectable		 1nbhD-3llcA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 8 SER A  79
PHE A  71
LEU A  42
LEU A  92
LEU A  96
 None
 1.14A 2bfpB-3llcA:
undetectable		 2bfpB-3llcA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 8 SER A  79
PHE A  71
LEU A  42
LEU A  92
 None
 0.95A 2bfpC-3llcA:
3.6		 2bfpC-3llcA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 9 LEU A 126
VAL A 228
ILE A 202
LEU A 109
VAL A 140
 EDO  A 273 (-4.0A)
None
EDO  A 271 ( 4.7A)
None
None
 1.06A 3oxzA-3llcA:
undetectable		 3oxzA-3llcA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 12 ASP A  58
ASP A  72
GLY A  77
ASP A  48
THR A  50
 None
 0.96A 3prsA-3llcA:
undetectable		 3prsA-3llcA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 5 TYR A 170
THR A 185
PHE A 184
ARG A  46
 None
 1.45A 3qelC-3llcA:
3.4		 3qelC-3llcA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 12 ASP A 147
ILE A 202
LEU A 231
GLY A 116
SER A 113
 None
EDO  A 271 ( 4.7A)
None
None
PG4  A 277 (-2.7A)
 1.33A 4djfB-3llcA:
undetectable		 4djfB-3llcA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 8 ARG A 250
VAL A 140
VAL A 241
GLY A 213
 None
 0.92A 4mk4A-3llcA:
4.6		 4mk4A-3llcA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 12 LEU A 238
GLY A 116
LEU A 120
VAL A 197
VAL A 236
 None
None
None
EDO  A 271 (-4.0A)
None
 1.22A 4wnwA-3llcA:
undetectable		 4wnwA-3llcA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 10 ALA A  68
ALA A  32
GLY A  65
ALA A  62
ASP A  59
 None
None
None
None
EDO  A 275 ( 4.0A)
 1.07A 5lf3H-3llcA:
undetectable
5lf3I-3llcA:
undetectable		 5lf3H-3llcA:
24.29
5lf3I-3llcA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 10 ALA A  68
ALA A  32
GLY A  65
ALA A  62
ASP A  59
 None
None
None
None
EDO  A 275 ( 4.0A)
 1.07A 5lf3V-3llcA:
undetectable
5lf3W-3llcA:
undetectable		 5lf3V-3llcA:
24.29
5lf3W-3llcA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 11 ALA A  68
ALA A  32
GLY A  65
ALA A  62
ASP A  59
 None
None
None
None
EDO  A 275 ( 4.0A)
 1.07A 5lf7H-3llcA:
undetectable
5lf7I-3llcA:
undetectable		 5lf7H-3llcA:
24.29
5lf7I-3llcA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 11 ALA A  68
ALA A  32
GLY A  65
ALA A  62
ASP A  59
 None
None
None
None
EDO  A 275 ( 4.0A)
 1.06A 5lf7V-3llcA:
undetectable
5lf7W-3llcA:
undetectable		 5lf7V-3llcA:
24.29
5lf7W-3llcA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 7 LEU A  55
ASP A  58
ALA A  61
LEU A  64
 EDO  A 275 ( 4.2A)
None
None
None
 0.93A 5nwvA-3llcA:
undetectable		 5nwvA-3llcA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 5 ILE A 153
PHE A 148
TYR A  45
ARG A  46
 PG4  A 277 ( 4.6A)
PG4  A 277 ( 4.1A)
None
None
 1.20A 5z84N-3llcA:
undetectable
5z84W-3llcA:
undetectable		 5z84N-3llcA:
20.12
5z84W-3llcA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 8 TYR A  45
GLY A 115
ILE A 118
ASP A  72
HIS A  76
 None
 1.35A 6ag0A-3llcA:
undetectable		 6ag0A-3llcA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 8 TYR A  45
GLY A 115
ILE A 118
HIS A  76
 None
 0.72A 6ag0C-3llcA:
undetectable		 6ag0C-3llcA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		5 / 12 GLY A  75
GLY A  77
ASP A  85
ASP A 191
ILE A  88
 None
 1.07A 6mhtA-3llcA:
3.7		 6mhtA-3llcA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3llc PUTATIVE HYDROLASE
(Agrobacterium
vitis) 		4 / 8 ASP A 255
ARG A 258
GLU A  56
ASP A  59
 None
None
EDO  A 275 (-3.5A)
EDO  A 275 ( 4.0A)
 1.19A 6mn4B-3llcA:
undetectable		 6mn4B-3llcA:
24.48