SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3llk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 PHE A 403
LEU A 330
PHE A 371
GLY A 317
GLY A 448
 None
 1.13A 1fe2A-3llkA:
undetectable		 1fe2A-3llkA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		3 / 3 ALA A 486
VAL A 501
TRP A 503
 None
None
FAD  A 550 (-3.7A)
 0.71A 1tkqB-3llkA:
undetectable		 1tkqB-3llkA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 LEU A 308
VAL A 347
GLY A 343
PHE A 413
LEU A 410
 None
 1.25A 3mecA-3llkA:
undetectable		 3mecA-3llkA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		4 / 8 HIS A 412
LEU A 436
MET A 464
TRP A 476
 FAD  A 550 (-3.1A)
None
None
None
 1.42A 3uzzB-3llkA:
undetectable		 3uzzB-3llkA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 GLY A 395
PHE A 498
VAL A 409
ASP A 303
TYR A 300
 None
None
FAD  A 550 ( 4.8A)
None
None
 1.35A 4a83A-3llkA:
undetectable		 4a83A-3llkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 10 HIS A 513
PHE A 530
THR A 527
ALA A 526
TRP A 478
 None
 1.43A 4twlA-3llkA:
undetectable		 4twlA-3llkA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 10 HIS A 513
PHE A 530
THR A 527
ALA A 526
TRP A 478
 None
 1.48A 4twlB-3llkA:
undetectable		 4twlB-3llkA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 ALA A 338
GLU A 380
LEU A 308
ILE A 311
PHE A 371
 None
 1.06A 5vlmE-3llkA:
undetectable		 5vlmE-3llkA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 ALA A 418
ALA A 419
GLN A 421
ALA A 432
LEU A 528
 None
 1.03A 5z12C-3llkA:
undetectable		 5z12C-3llkA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		5 / 12 ALA A 418
ALA A 419
GLN A 421
ALA A 432
LEU A 528
 None
 1.05A 6a60D-3llkA:
undetectable		 6a60D-3llkA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3llk SULFHYDRYL OXIDASE 1
(Homo
sapiens) 		3 / 3 LYS A 298
SER A 536
SER A 538
 None
 1.02A 6gbfA-3llkA:
undetectable		 6gbfA-3llkA:
20.90