SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3llq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		4 / 7 PHE A 143
LEU A  15
VAL A  47
THR A  46
 None
 0.96A 2qblA-3llqA:
undetectable		 2qblA-3llqA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		4 / 8 LEU A 144
PRO A 185
SER A 182
VAL A  85
 None
 1.15A 2qd2A-3llqA:
undetectable		 2qd2A-3llqA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 9 PHE A  43
VAL A  47
GLY A 165
VAL A  16
GLN A 191
 None
 1.45A 3kmoA-3llqA:
undetectable		 3kmoA-3llqA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		3 / 3 ASN A 184
ASN A 117
GLU A 136
 None
 0.85A 3kpdB-3llqA:
undetectable		 3kpdB-3llqA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 9 VAL A  24
PHE A  25
PHE A 194
ALA A  98
VAL A  16
 None
 1.25A 3me6D-3llqA:
undetectable		 3me6D-3llqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 12 PHE A  43
PHE A  62
LEU A  15
SER A  67
LEU A 168
 None
 1.13A 3nrrA-3llqA:
undetectable		 3nrrA-3llqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 12 GLY A  18
ILE A 171
GLY A  44
ALA A  42
SER A 175
 None
 1.09A 3sudB-3llqA:
undetectable		 3sudB-3llqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		3 / 3 TYR A  52
LEU A   6
LYS A   4
 None
 0.79A 3sueD-3llqA:
undetectable		 3sueD-3llqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		4 / 8 ALA A  65
ASN A  63
ALA A 186
THR A 189
 None
 0.93A 3t3sD-3llqA:
undetectable		 3t3sD-3llqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		3 / 3 TYR A  84
LYS A   1
LYS A   4
 None
 1.25A 5dbyA-3llqA:
undetectable		 5dbyA-3llqA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 10 ALA A 160
THR A 151
SER A 150
GLY A  55
ALA A  51
 None
 1.38A 5l66K-3llqA:
undetectable
5l66L-3llqA:
undetectable		 5l66K-3llqA:
18.97
5l66L-3llqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3llq AQUAPORIN Z 2
(Agrobacterium
fabrum) 		5 / 10 ALA A 160
THR A 151
SER A 150
GLY A  55
ALA A  51
 None
 1.39A 5l66Y-3llqA:
undetectable
5l66Z-3llqA:
undetectable		 5l66Y-3llqA:
18.97
5l66Z-3llqA:
21.98