SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3llr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		5 / 12 SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
 None
 1.40A 2vdyB-3llrA:
undetectable		 2vdyB-3llrA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		3 / 3 TRP A  39
VAL A  37
TRP A  40
 None
 1.07A 3zq8C-3llrA:
undetectable
3zq8D-3llrA:
undetectable		 3zq8C-3llrA:
7.83
3zq8D-3llrA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		5 / 11 ALA A 102
SER A 103
PHE A  80
ILE A 133
ASN A 129
 None
 1.35A 4bb2A-3llrA:
undetectable
4bb2B-3llrA:
undetectable		 4bb2A-3llrA:
16.81
4bb2B-3llrA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		6 / 12 ALA A 102
SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
 None
 1.49A 4c49A-3llrA:
undetectable		 4c49A-3llrA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		5 / 12 SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
 None
 1.44A 4c49C-3llrA:
undetectable		 4c49C-3llrA:
18.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens) 		5 / 7 PHE A  29
TRP A  32
TRP A  56
ASP A  59
LYS A  61
 BTB  A 154 (-3.2A)
BTB  A 154 (-3.6A)
BTB  A 154 (-3.4A)
BTB  A 154 (-2.7A)
BTB  A 154 (-3.6A)
 1.00A 5nr3A-3llrA:
25.1		 5nr3A-3llrA:
51.61