SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3llv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3llv EXOPOLYPHOSPHATASE-R
ELATED PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 LEU A  66
VAL A  74
TYR A   7
TYR A  63
 None
 1.14A 4b3qA-3llvA:
undetectable		 4b3qA-3llvA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3llv EXOPOLYPHOSPHATASE-R
ELATED PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 102
ASP A  36
ASP A  56
 PO4  A 142 (-2.7A)
None
None
 0.79A 4kicB-3llvA:
undetectable		 4kicB-3llvA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3llv EXOPOLYPHOSPHATASE-R
ELATED PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  21
GLY A  78
ALA A  17
GLU A  82
PHE A  83
 None
None
PO4  A 142 (-3.0A)
None
None
 1.26A 5x6yC-3llvA:
undetectable		 5x6yC-3llvA:
11.29