SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 8 TYR A  61
ASN A  98
GLY A  63
THR A 120
 None
 0.83A 1ykiA-3lm2A:
undetectable
1ykiB-3lm2A:
undetectable		 1ykiA-3lm2A:
20.52
1ykiB-3lm2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 8 THR A 120
TYR A  61
ASN A  98
GLY A  63
 None
 0.81A 1ykiA-3lm2A:
undetectable
1ykiB-3lm2A:
undetectable		 1ykiA-3lm2A:
20.52
1ykiB-3lm2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 8 TYR A  61
ASN A  98
GLY A  63
THR A 120
 None
 0.81A 1ykiC-3lm2A:
undetectable
1ykiD-3lm2A:
undetectable		 1ykiC-3lm2A:
20.52
1ykiD-3lm2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 8 THR A 120
TYR A  61
ASN A  98
GLY A  63
 None
 0.81A 1ykiC-3lm2A:
undetectable
1ykiD-3lm2A:
undetectable		 1ykiC-3lm2A:
20.52
1ykiD-3lm2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		6 / 12 LEU A 114
GLY A 123
ALA A 100
ASP A  99
GLY A 189
VAL A 185
 None
EDO  A 227 ( 4.8A)
EDO  A 227 (-3.9A)
EDO  A 227 (-4.3A)
EDO  A 227 (-3.1A)
None
 1.42A 2o4lB-3lm2A:
undetectable		 2o4lB-3lm2A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 117
GLY A 189
VAL A 186
LEU A 116
VAL A 172
 EDO  A 227 (-3.6A)
EDO  A 227 (-3.1A)
None
None
None
 0.89A 2yqzB-3lm2A:
undetectable		 2yqzB-3lm2A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 6 GLY A 205
GLN A 103
ILE A 187
VAL A 186
 None
EDO  A 227 (-2.3A)
None
None
 1.12A 3kvvF-3lm2A:
undetectable		 3kvvF-3lm2A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		3 / 3 LYS A 146
TYR A 142
ARG A 143
 None
 1.29A 4gc9A-3lm2A:
undetectable		 4gc9A-3lm2A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A 104
GLY A 123
GLY A 117
LEU A 118
ALA A 125
 None
EDO  A 227 ( 4.8A)
EDO  A 227 (-3.6A)
None
None
 1.08A 4lg1A-3lm2A:
undetectable		 4lg1A-3lm2A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A 104
GLY A 123
GLY A 117
LEU A 118
ALA A 125
 None
EDO  A 227 ( 4.8A)
EDO  A 227 (-3.6A)
None
None
 1.09A 4lg1B-3lm2A:
undetectable		 4lg1B-3lm2A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		5 / 12 ALA A 104
GLY A 123
GLY A 117
LEU A 118
ALA A 125
 None
EDO  A 227 ( 4.8A)
EDO  A 227 (-3.6A)
None
None
 1.09A 4lg1C-3lm2A:
undetectable		 4lg1C-3lm2A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		4 / 7 GLU A  73
TYR A  86
GLY A  38
GLY A  80
 None
 0.85A 4rdxA-3lm2A:
undetectable		 4rdxA-3lm2A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		3 / 3 VAL A  42
TYR A  86
ALA A  89
 None
 0.35A 4ybnA-3lm2A:
undetectable		 4ybnA-3lm2A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3lm2 PUTATIVE KINASE
(Agrobacterium
fabrum) 		5 / 11 ILE A  57
LEU A   8
THR A  23
LEU A 217
PHE A 215
 None
 1.38A 6hupA-3lm2A:
undetectable
6hupB-3lm2A:
undetectable		 6hupA-3lm2A:
14.73
6hupB-3lm2A:
16.29