SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		6 / 12 GLY A 202
THR A 162
ILE A 195
ALA A 309
GLY A 308
ILE A 322
 None
 1.30A 1bx4A-3lm6A:
undetectable		 1bx4A-3lm6A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 7 PHE A 103
ALA A 134
LEU A 133
VAL A  63
 None
 0.92A 1hk2A-3lm6A:
undetectable		 1hk2A-3lm6A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 ALA A 283
SER A 282
THR A 112
SER A 288
ALA A  66
 None
 0.96A 1nt2A-3lm6A:
undetectable		 1nt2A-3lm6A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 GLY A 169
ALA A 283
SER A 282
SER A 288
ALA A  66
 None
 1.15A 1nt2A-3lm6A:
undetectable		 1nt2A-3lm6A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		6 / 12 ASP A 260
ASP A 259
ILE A 246
PRO A 253
ALA A 224
ILE A 230
 None
 1.45A 1rl8A-3lm6A:
undetectable		 1rl8A-3lm6A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		6 / 12 ASP A 260
ASP A 259
ILE A 246
PRO A 253
ALA A 224
ILE A 230
 None
 1.45A 1rl8B-3lm6A:
undetectable		 1rl8B-3lm6A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 ALA A  20
PHE A 331
SER A 113
LEU A 231
VAL A 285
 None
 1.32A 1u72A-3lm6A:
undetectable		 1u72A-3lm6A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 6 LEU A 123
PHE A 128
ALA A 129
LEU A 104
 None
 0.98A 1ukbA-3lm6A:
undetectable		 1ukbA-3lm6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ARG A 295
VAL A 284
THR A  22
 None
 0.87A 2nnkA-3lm6A:
undetectable		 2nnkA-3lm6A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 5 LEU A 264
GLN A 293
THR A 232
HIS A 258
 None
 1.24A 2zj0C-3lm6A:
undetectable		 2zj0C-3lm6A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 LEU A  81
ALA A 185
VAL A 171
PHE A 291
LEU A 294
 None
 1.24A 3b0wB-3lm6A:
undetectable		 3b0wB-3lm6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 5 LEU A 264
GLN A 293
THR A 232
HIS A 258
 None
 1.32A 3ce6B-3lm6A:
undetectable		 3ce6B-3lm6A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 VAL A 284
TYR A 266
PRO A  32
PHE A  37
 None
 1.32A 3d91B-3lm6A:
0.0		 3d91B-3lm6A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 LEU A 263
GLY A 202
GLY A 237
SER A 236
HIS A 258
 None
 1.15A 3e23A-3lm6A:
undetectable		 3e23A-3lm6A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 GLY A 126
VAL A 124
LEU A 104
MET A 106
ILE A  15
 None
 1.24A 3h52B-3lm6A:
undetectable		 3h52B-3lm6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ARG A 295
VAL A 284
THR A  22
 None
 0.84A 3k4vA-3lm6A:
undetectable		 3k4vA-3lm6A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ARG A 295
VAL A 284
THR A  22
 None
 0.78A 3k4vD-3lm6A:
undetectable		 3k4vD-3lm6A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 11 SER A 277
ALA A 109
GLY A 308
THR A 307
ASP A 260
 None
 1.29A 3mg0H-3lm6A:
undetectable
3mg0I-3lm6A:
undetectable		 3mg0H-3lm6A:
22.35
3mg0I-3lm6A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ARG A 295
VAL A 284
THR A  22
 None
 0.79A 3nduD-3lm6A:
undetectable		 3nduD-3lm6A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 8 LEU A  33
ALA A  23
THR A  22
GLY A 262
 None
 0.95A 3ny4A-3lm6A:
undetectable		 3ny4A-3lm6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 6 VAL A 171
ASN A  18
TYR A 287
ILE A 182
 None
 1.14A 3q5sA-3lm6A:
1.8		 3q5sA-3lm6A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ARG A 295
VAL A 284
THR A  22
 None
 0.84A 3tl9A-3lm6A:
undetectable		 3tl9A-3lm6A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 8 ILE A 213
PHE A 303
SER A 113
GLY A 328
 None
 0.80A 4acbC-3lm6A:
undetectable		 4acbC-3lm6A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 ALA A 283
SER A 282
VAL A 285
THR A  40
PHE A  37
 None
 1.11A 4c49A-3lm6A:
undetectable		 4c49A-3lm6A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.35A 4lvcA-3lm6A:
undetectable		 4lvcA-3lm6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.34A 4lvcC-3lm6A:
undetectable		 4lvcC-3lm6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 VAL A 171
VAL A 285
MET A 114
ALA A 120
PHE A 331
 None
 1.36A 4nc3A-3lm6A:
undetectable		 4nc3A-3lm6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 11 SER A 277
ALA A 109
GLY A 308
THR A 307
ASP A 260
 None
 1.32A 5bxnV-3lm6A:
undetectable
5bxnW-3lm6A:
undetectable		 5bxnV-3lm6A:
22.19
5bxnW-3lm6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 ILE A 265
MET A 114
ASP A 260
 None
 0.79A 5h2uA-3lm6A:
undetectable		 5h2uA-3lm6A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		6 / 12 GLY A 202
THR A 162
ILE A 195
ALA A 309
GLY A 308
ILE A 322
 None
 1.35A 5kb6A-3lm6A:
undetectable		 5kb6A-3lm6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 10 ALA A 135
THR A 136
ALA A  20
GLY A  21
ALA A  62
 None
 1.18A 5lf3H-3lm6A:
undetectable
5lf3I-3lm6A:
undetectable		 5lf3H-3lm6A:
23.23
5lf3I-3lm6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 10 ALA A 135
THR A 136
ALA A  20
GLY A  21
ALA A  62
 None
 1.20A 5lf3V-3lm6A:
undetectable
5lf3W-3lm6A:
undetectable		 5lf3V-3lm6A:
23.23
5lf3W-3lm6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.39A 5m5kA-3lm6A:
undetectable		 5m5kA-3lm6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.40A 5m5kC-3lm6A:
undetectable		 5m5kC-3lm6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 THR A 112
MET A 114
HIS A 327
 None
 0.94A 5uunA-3lm6A:
undetectable		 5uunA-3lm6A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLU A 115
THR A 116
THR A  91
LEU A  85
 None
 1.41A 5v96A-3lm6A:
undetectable		 5v96A-3lm6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLU A 115
THR A 116
THR A  91
LEU A  85
 None
 1.40A 5v96B-3lm6A:
undetectable		 5v96B-3lm6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLU A 115
THR A 116
THR A  91
LEU A  85
 None
 1.40A 5v96C-3lm6A:
undetectable		 5v96C-3lm6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 4 GLU A 115
THR A 116
THR A  91
LEU A  85
 None
 1.41A 5v96D-3lm6A:
undetectable		 5v96D-3lm6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		3 / 3 SER A 184
HIS A 216
TYR A 227
 None
 0.71A 5y2tA-3lm6A:
undetectable		 5y2tA-3lm6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.35A 6gbnD-3lm6A:
undetectable		 6gbnD-3lm6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 3lm6 STAGE V SPORULATION
PROTEIN AD
(Bacillus
subtilis) 		5 / 12 GLY A 276
GLY A 262
LEU A 263
GLN A 270
PRO A  32
 None
 1.11A 6gngB-3lm6A:
undetectable		 6gngB-3lm6A:
20.32