SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 7 LEU A  40
THR A 229
ASN A  15
TYR A 218
 None
 1.09A 1afsA-3lm7A:
6.6		 1afsA-3lm7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 7 LEU A  40
THR A 229
ASN A  15
TYR A 218
 None
 1.08A 1afsB-3lm7A:
6.7		 1afsB-3lm7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 10 ASN A 114
LEU A  65
LEU A  17
TYR A 218
THR A 190
 None
 1.38A 1zucA-3lm7A:
undetectable		 1zucA-3lm7A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 12 SER A 102
ARG A  75
VAL A  95
GLN A  94
SER A  41
 None
 1.42A 2o7oA-3lm7A:
undetectable		 2o7oA-3lm7A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 6 LEU A 237
VAL A 241
LYS A 242
ILE A 217
 None
 0.80A 2piwA-3lm7A:
undetectable		 2piwA-3lm7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 12 SER A 102
ARG A  75
VAL A  95
GLN A  94
SER A  41
 None
 1.46A 2xpvA-3lm7A:
undetectable		 2xpvA-3lm7A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 12 SER A 102
ARG A  75
VAL A  95
GLN A  94
SER A  41
 None
 1.43A 2xpwA-3lm7A:
undetectable		 2xpwA-3lm7A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		3 / 3 ASP A 233
ASP A 223
ASP A 194
 None
 0.77A 3douA-3lm7A:
undetectable		 3douA-3lm7A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 7 ILE A 221
LEU A 237
ALA A  30
ALA A  31
 None
 0.83A 3r9tB-3lm7A:
undetectable		 3r9tB-3lm7A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 9 THR A 190
LEU A  17
VAL A 234
LEU A 237
ILE A 221
 None
 1.00A 4r38C-3lm7A:
undetectable		 4r38C-3lm7A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 12 LEU A 187
VAL A 213
GLY A 209
ALA A 208
ILE A 204
 None
 0.76A 4xdrA-3lm7A:
undetectable		 4xdrA-3lm7A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 6 GLY A  98
THR A  97
SER A  77
VAL A  95
 None
 1.03A 5ewuA-3lm7A:
undetectable		 5ewuA-3lm7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		5 / 12 VAL A 144
ILE A 148
ALA A 149
LYS A 152
PHE A 185
 None
 0.84A 5j2tC-3lm7A:
undetectable		 5j2tC-3lm7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 7 ILE A 221
GLU A 232
ASP A 223
ASN A  23
 None
 1.07A 5n5dA-3lm7A:
2.3		 5n5dA-3lm7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3lm7 PUTATIVE
4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE /
2-DEHYDRO-3-DEOXYPHO
SPHOGLUCONATE
ALDOLASE
(Yersinia
enterocolitica) 		4 / 7 ALA A  58
ILE A  83
GLN A  86
VAL A  87
 None
 0.89A 6cduF-3lm7A:
undetectable
6cduJ-3lm7A:
undetectable		 6cduF-3lm7A:
21.52
6cduJ-3lm7A:
21.52