SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 10 ALA A 132
LEU A  67
ALA A  66
PHE A  80
ILE A  77
 None
 0.91A 1g5yC-3lmaA:
undetectable		 1g5yC-3lmaA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 LEU A  81
ALA A 118
ILE A 117
SER A 121
 None
 1.10A 2othA-3lmaA:
undetectable		 2othA-3lmaA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A 215
THR A 186
THR A 307
LEU A 243
 None
 1.34A 3ce6A-3lmaA:
undetectable		 3ce6A-3lmaA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A 215
THR A 186
THR A 307
LEU A 243
 None
 1.30A 3ce6C-3lmaA:
undetectable		 3ce6C-3lmaA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 9 LEU A 173
VAL A  17
VAL A 304
ILE A 294
PHE A 287
 None
 1.05A 3cs9C-3lmaA:
undetectable		 3cs9C-3lmaA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 4 VAL A 284
TYR A 266
PRO A  32
PHE A  37
 None
 1.30A 3d91B-3lmaA:
0.0		 3d91B-3lmaA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 8 LEU A  33
ALA A  23
THR A  22
GLY A 262
 None
 0.95A 3ny4A-3lmaA:
undetectable		 3ny4A-3lmaA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 12 SER A  19
VAL A  17
ILE A 117
SER A 113
PHE A 331
 None
 1.16A 4c49D-3lmaA:
undetectable		 4c49D-3lmaA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 12 ALA A  66
PHE A 291
LEU A 303
PHE A 331
THR A 286
 None
 1.35A 4iarA-3lmaA:
undetectable		 4iarA-3lmaA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.30A 4lvcA-3lmaA:
undetectable		 4lvcA-3lmaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.29A 4lvcC-3lmaA:
undetectable		 4lvcC-3lmaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 7 GLU A 115
GLY A 108
SER A 111
GLY A 308
 None
 0.92A 5e26A-3lmaA:
undetectable
5e26B-3lmaA:
undetectable		 5e26A-3lmaA:
22.86
5e26B-3lmaA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 8 GLU A 115
GLY A 108
SER A 111
GLY A 308
 None
 0.90A 5e26C-3lmaA:
2.4
5e26D-3lmaA:
2.1		 5e26C-3lmaA:
22.86
5e26D-3lmaA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 7 LEU A 235
THR A 232
ILE A 213
LEU A 303
 None
 0.97A 5fxtA-3lmaA:
undetectable		 5fxtA-3lmaA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLU A 115
GLY A 108
SER A 111
GLY A 308
 None
 0.99A 5kprA-3lmaA:
undetectable		 5kprA-3lmaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 4 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.33A 5m5kA-3lmaA:
undetectable		 5m5kA-3lmaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 4 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.35A 5m5kC-3lmaA:
undetectable		 5m5kC-3lmaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 9 ALA A 118
ILE A 117
ILE A 124
ALA A 132
LEU A 173
 None
 1.13A 5mvmA-3lmaA:
undetectable
5mvmE-3lmaA:
undetectable		 5mvmA-3lmaA:
12.87
5mvmE-3lmaA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		3 / 3 THR A 112
MET A 114
HIS A 327
 None
 0.97A 5uunA-3lmaA:
undetectable		 5uunA-3lmaA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 12 LEU A 133
GLY A 169
ALA A 134
GLU A  28
THR A  22
 None
 1.21A 5x6yC-3lmaA:
undetectable		 5x6yC-3lmaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		3 / 3 SER A 184
HIS A 216
TYR A 227
 None
 0.67A 5y2tA-3lmaA:
undetectable		 5y2tA-3lmaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 9 ALA A 306
SER A 111
ALA A 280
GLY A 233
GLY A 278
 None
 1.21A 6bklE-3lmaA:
undetectable
6bklF-3lmaA:
undetectable
6bklG-3lmaA:
undetectable
6bklH-3lmaA:
undetectable		 6bklE-3lmaA:
7.67
6bklF-3lmaA:
7.67
6bklG-3lmaA:
7.67
6bklH-3lmaA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		5 / 12 ALA A 204
GLY A 308
ILE A 325
ILE A 315
ILE A 322
 None
 0.90A 6dh3A-3lmaA:
undetectable		 6dh3A-3lmaA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.32A 6gbnA-3lmaA:
undetectable		 6gbnA-3lmaA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 5 GLN A   7
THR A 186
THR A 232
LEU A 247
 None
 1.32A 6gbnD-3lmaA:
undetectable		 6gbnD-3lmaA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 6 TYR A 266
GLU A  28
CYH A  46
GLU A  43
 None
 0.92A 6mn5A-3lmaA:
undetectable		 6mn5A-3lmaA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 7 TYR A 266
GLU A  28
CYH A  46
GLU A  43
 None
 0.77A 6mn5B-3lmaA:
undetectable		 6mn5B-3lmaA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)
(Bacillus
licheniformis) 		4 / 6 TYR A 266
GLU A  28
CYH A  46
GLU A  43
 None
 0.93A 6mn5C-3lmaA:
undetectable		 6mn5C-3lmaA:
12.46