SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		3 / 3 TRP A  70
ALA A 160
VAL A  88
 None
 0.91A 1c4dA-3lmbA:
undetectable
1c4dB-3lmbA:
undetectable		 1c4dA-3lmbA:
6.45
1c4dB-3lmbA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		3 / 3 GLN A 158
ILE A 145
HIS A 108
 None
 0.70A 1fm9A-3lmbA:
undetectable		 1fm9A-3lmbA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		3 / 3 GLN A 158
ILE A 145
HIS A 108
 None
 0.67A 1k74A-3lmbA:
undetectable		 1k74A-3lmbA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		4 / 4 GLY A  37
GLU A  79
ASP A   8
ASP A  38
 None
 1.02A 3mb5A-3lmbA:
undetectable		 3mb5A-3lmbA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		4 / 6 LEU A  61
SER A 152
PRO A 151
GLU A 146
 None
 1.20A 5b8iA-3lmbA:
undetectable		 5b8iA-3lmbA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		5 / 12 ALA A 134
PHE A 155
GLY A 157
GLY A  91
LEU A  22
 None
 0.98A 5ul4A-3lmbA:
2.2		 5ul4A-3lmbA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3lmb UNCHARACTERIZED
PROTEIN
(Oleispira
antarctica) 		5 / 9 PHE A 118
ALA A 128
ALA A 160
THR A  89
LEU A 132
 None
 1.43A 6ay6A-3lmbA:
undetectable		 6ay6A-3lmbA:
15.40