SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 ILE A 215
GLY A 216
ALA A 217
SER A 225
LEU A 224
 None
None
None
CL  A 585 ( 4.4A)
None
 1.01A 1eqhA-3lmmA:
undetectable		 1eqhA-3lmmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 GLN A 455
TYR A 430
ARG A 378
 None
 0.89A 1gtbA-3lmmA:
undetectable		 1gtbA-3lmmA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ARG A 431
ARG A 112
ARG A 426
 None
 1.05A 1l7fA-3lmmA:
undetectable		 1l7fA-3lmmA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ARG A 431
ARG A 112
ARG A 426
 None
 1.06A 1l7hA-3lmmA:
undetectable		 1l7hA-3lmmA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ASP A 429
TYR A 430
ASP A 377
GLU A 466
 None
 1.33A 1rjdC-3lmmA:
undetectable		 1rjdC-3lmmA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 LEU A  84
VAL A 119
GLY A 108
VAL A 134
ILE A 132
 None
 0.95A 1t3rB-3lmmA:
undetectable		 1t3rB-3lmmA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 TRP A 150
GLU A 163
TYR A 167
 None
 1.11A 2a3aA-3lmmA:
undetectable		 2a3aA-3lmmA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 ARG A 197
LEU A 193
LEU A 211
PHE A 203
 None
 0.93A 2dysC-3lmmA:
undetectable
2dysJ-3lmmA:
undetectable		 2dysC-3lmmA:
17.18
2dysJ-3lmmA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ARG A 352
GLU A 142
ASN A  77
ALA A  73
 None
 1.14A 2ejfB-3lmmA:
undetectable		 2ejfB-3lmmA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 ARG A 352
GLU A 142
ASN A  77
ALA A  73
 None
 1.20A 2ejgA-3lmmA:
undetectable		 2ejgA-3lmmA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 PHE A 232
SER A 263
ALA A 194
LEU A 193
 None
 0.78A 2o01A-3lmmA:
undetectable		 2o01A-3lmmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 LEU A 271
TYR A 270
GLN A 273
 None
 0.49A 2wekA-3lmmA:
undetectable		 2wekA-3lmmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 VAL A 115
ASN A  77
TRP A 164
 None
 0.89A 2y00B-3lmmA:
undetectable		 2y00B-3lmmA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 VAL A 134
ASN A  77
TRP A 164
 None
 0.95A 2y00B-3lmmA:
undetectable		 2y00B-3lmmA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ASP A 328
THR A 283
GLU A 295
 None
 0.65A 2zifB-3lmmA:
undetectable		 2zifB-3lmmA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 LEU A  84
VAL A 119
GLY A 108
VAL A 134
ILE A 132
 None
 0.98A 4dqhA-3lmmA:
undetectable		 4dqhA-3lmmA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 GLY A 407
SER A 329
TRP A 324
 None
 0.92A 4e7cD-3lmmA:
2.4		 4e7cD-3lmmA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 ARG A 462
GLN A 107
GLY A 108
THR A 111
 None
 0.92A 4k87A-3lmmA:
undetectable		 4k87A-3lmmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 GLY A 214
ARG A 161
ALA A 365
LEU A 362
ILE A 320
 None
None
None
CL  A 585 ( 3.8A)
None
 1.08A 4kt0A-3lmmA:
undetectable
4kt0J-3lmmA:
undetectable		 4kt0A-3lmmA:
22.31
4kt0J-3lmmA:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 VAL A 401
SER A 335
ASN A 307
GLN A 372
ASN A 351
 None
 1.49A 4kuoA-3lmmA:
undetectable		 4kuoA-3lmmA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 PHE A 232
SER A 263
ALA A 194
LEU A 193
 None
 0.96A 4rkuA-3lmmA:
undetectable
4rkuJ-3lmmA:
undetectable		 4rkuA-3lmmA:
21.07
4rkuJ-3lmmA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 PHE A 232
SER A 263
ALA A 194
LEU A 193
 None
 0.97A 4xk8A-3lmmA:
undetectable		 4xk8A-3lmmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 PHE A 232
SER A 263
ALA A 194
LEU A 193
 None
 0.96A 4xk8a-3lmmA:
undetectable		 4xk8a-3lmmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 11 ILE A 296
GLU A 326
TRP A 324
LEU A 242
LEU A 275
 None
 1.48A 4yvpA-3lmmA:
undetectable		 4yvpA-3lmmA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 366
GLY A 367
ARG A 364
GLU A 272
LEU A 231
 None
 1.35A 5czyA-3lmmA:
undetectable		 5czyA-3lmmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ARG A 197
LEU A 193
LEU A 211
PHE A 203
 None
 1.09A 5iy5P-3lmmA:
undetectable
5iy5W-3lmmA:
undetectable		 5iy5P-3lmmA:
17.01
5iy5W-3lmmA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 SER A 225
LEU A 224
GLY A 228
PHE A 232
LEU A 212
 CL  A 585 ( 4.4A)
None
None
None
None
 1.40A 5jo9A-3lmmA:
undetectable		 5jo9A-3lmmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 VAL A  31
PHE A  42
ILE A 132
ALA A 131
VAL A  86
 None
 1.16A 5n0sB-3lmmA:
1.1		 5n0sB-3lmmA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ARG A 213
ARG A 169
ARG A 161
 None
 0.98A 5vcgA-3lmmA:
undetectable		 5vcgA-3lmmA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 VAL A 401
HIS A 311
ILE A 310
THR A 403
 None
 0.83A 5vkqA-3lmmA:
undetectable
5vkqD-3lmmA:
undetectable		 5vkqA-3lmmA:
16.44
5vkqD-3lmmA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ARG A 197
LEU A 193
LEU A 211
PHE A 203
 None
 1.04A 5w97C-3lmmA:
undetectable
5w97J-3lmmA:
undetectable		 5w97C-3lmmA:
17.18
5w97J-3lmmA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ARG A 197
LEU A 193
LEU A 211
PHE A 203
 None
 1.04A 5x19C-3lmmA:
undetectable
5x19J-3lmmA:
undetectable		 5x19C-3lmmA:
17.18
5x19J-3lmmA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ARG A 197
LEU A 193
LEU A 211
PHE A 203
 None
 1.02A 5x1fC-3lmmA:
undetectable
5x1fJ-3lmmA:
undetectable		 5x1fC-3lmmA:
17.18
5x1fJ-3lmmA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 10 ILE A  85
ILE A 113
ALA A  69
LEU A  68
ALA A  64
 None
 1.46A 5zjiB-3lmmA:
undetectable		 5zjiB-3lmmA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 9 LEU A 105
ILE A 132
ARG A 106
VAL A  72
ILE A 109
 None
 0.94A 6ef6A-3lmmA:
undetectable		 6ef6A-3lmmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 PHE A 110
ARG A 106
GLN A 107
 None
 1.12A 6g1pB-3lmmA:
undetectable		 6g1pB-3lmmA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3lmm UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 10 LEU A 439
VAL A 435
ILE A 447
ALA A 481
LEU A 465
 None
 1.37A 6h1lA-3lmmA:
undetectable		 6h1lA-3lmmA:
23.36