SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lmz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 6 ASP A 169
ASN A 196
ASP A 193
TYR A 207
 None
 1.37A 1hpkA-3lmzA:
undetectable		 1hpkA-3lmzA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 1jffB-3lmzA:
undetectable		 1jffB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 7 ASP A 221
VAL A 219
GLY A 161
ILE A 164
 None
 0.75A 1t7iB-3lmzA:
undetectable		 1t7iB-3lmzA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 7 ASP A 221
VAL A 219
GLY A 161
ILE A 164
 None
 0.78A 1t7jB-3lmzA:
undetectable		 1t7jB-3lmzA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 2hxfB-3lmzA:
undetectable		 2hxfB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 2hxhB-3lmzA:
undetectable		 2hxhB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 218
ASP A 221
ASP A 237
 None
 0.78A 2igtB-3lmzA:
undetectable		 2igtB-3lmzA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 5 LEU A  58
ASP A  77
MET A  48
LEU A  65
 None
 1.20A 2jfaA-3lmzA:
undetectable		 2jfaA-3lmzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 2p4nB-3lmzA:
undetectable		 2p4nB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 5 LEU A  58
ASP A  77
MET A  48
LEU A  65
 None
 1.25A 2qxsA-3lmzA:
undetectable		 2qxsA-3lmzA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 5 LEU A  58
ASP A  77
MET A  48
LEU A  65
 None
 1.24A 2qxsB-3lmzA:
undetectable		 2qxsB-3lmzA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 2wbeB-3lmzA:
undetectable		 2wbeB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.18A 3dcoB-3lmzA:
undetectable		 3dcoB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.17A 3edlB-3lmzA:
undetectable		 3edlB-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 4 ARG A 183
ASP A 145
ASP A 181
PRO A 182
 None
 1.50A 3fgrB-3lmzA:
undetectable		 3fgrB-3lmzA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 VAL A 127
LEU A  62
LEU A  58
THR A  61
GLY A 107
 None
 1.15A 3iz0B-3lmzA:
undetectable		 3iz0B-3lmzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 PRO A 182
LYS A 149
ARG A 210
PRO A 136
ASP A 145
 None
 1.01A 3m6vB-3lmzA:
undetectable		 3m6vB-3lmzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 8 ASP A 221
VAL A 219
GLY A 161
ILE A 164
 None
 0.78A 3nu9A-3lmzA:
undetectable		 3nu9A-3lmzA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 8 PRO A 136
HIS A 176
ILE A 157
ILE A 184
 None
 1.03A 3sfeB-3lmzA:
undetectable
3sfeC-3lmzA:
undetectable		 3sfeB-3lmzA:
21.43
3sfeC-3lmzA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 8 VAL A 144
TYR A 151
ILE A 184
ILE A 132
 None
PEG  A   2 ( 4.1A)
None
None
 1.05A 4afgD-3lmzA:
undetectable
4afgE-3lmzA:
undetectable		 4afgD-3lmzA:
21.15
4afgE-3lmzA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		5 / 12 ILE A  70
LEU A  65
ALA A  49
SER A 255
LEU A 256
 None
 1.10A 4m11A-3lmzA:
undetectable		 4m11A-3lmzA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		3 / 3 HIS A  79
LYS A  76
PHE A  78
 None
CIT  A   1 (-2.9A)
None
 0.93A 5klaA-3lmzA:
undetectable		 5klaA-3lmzA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 3lmz PUTATIVE SUGAR
ISOMERASE
(Parabacteroides
distasonis) 		4 / 5 THR A  52
HIS A 215
ASP A 189
HIS A 158
 None
None
None
CIT  A   1 (-3.7A)
 1.38A 6dchA-3lmzA:
undetectable		 6dchA-3lmzA:
20.94