SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ln6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		4 / 4 THR A 384
LEU A 191
LEU A 371
GLN A 368
 None
 1.23A 1fbmA-3ln6A:
undetectable		 1fbmA-3ln6A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		5 / 12 GLU A 626
ARG A 614
ALA A 590
GLU A 631
ARG A 655
 None
 1.22A 1nncA-3ln6A:
undetectable		 1nncA-3ln6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		3 / 3 PRO A 105
LEU A  28
ARG A  29
 None
 0.84A 3aqiB-3ln6A:
undetectable		 3aqiB-3ln6A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		3 / 3 MET A 688
VAL A 695
GLU A 686
 None
 0.74A 3c6gA-3ln6A:
undetectable		 3c6gA-3ln6A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		3 / 3 SER A 141
SER A 102
HIS A 144
 None
 0.84A 3mzeA-3ln6A:
undetectable		 3mzeA-3ln6A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		5 / 10 THR A 384
PRO A 196
HIS A 336
GLY A 387
ALA A 386
 None
 1.49A 3pp7B-3ln6A:
undetectable		 3pp7B-3ln6A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		3 / 3 HIS A  94
HIS A 410
ILE A  92
 None
 0.74A 3u52A-3ln6A:
undetectable
3u52C-3ln6A:
undetectable		 3u52A-3ln6A:
21.32
3u52C-3ln6A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		4 / 7 GLY A 663
GLY A 664
ASN A 592
GLU A 623
 None
 1.07A 4fgkB-3ln6A:
undetectable		 4fgkB-3ln6A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		5 / 12 GLU A 626
ARG A 614
ALA A 590
GLU A 631
ARG A 655
 None
 1.28A 4i00A-3ln6A:
undetectable		 4i00A-3ln6A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		3 / 3 SER A 661
GLU A 572
GLU A 565
 SO4  A 751 (-3.1A)
None
None
 0.80A 4ymgB-3ln6A:
undetectable		 4ymgB-3ln6A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		4 / 6 ARG A  79
ALA A  71
PRO A  69
PHE A 444
 None
 1.36A 5odqA-3ln6A:
undetectable		 5odqA-3ln6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB
(Streptococcus
agalactiae) 		4 / 6 LEU A 188
PHE A 284
ASP A 285
HIS A 144
 None
 0.88A 5om3A-3ln6A:
undetectable
5om3B-3ln6A:
undetectable		 5om3A-3ln6A:
7.85
5om3B-3ln6A:
4.89