SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ln9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
3 / 3 ALA A  98
VAL A 104
TRP A 105
None
GOL  A 138 (-3.9A)
None
0.84A 1nt6A-3ln9A:
undetectable
1nt6A-3ln9A:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
3 / 3 ALA A  98
VAL A 104
TRP A 105
None
GOL  A 138 (-3.9A)
None
0.84A 1nt6B-3ln9A:
undetectable
1nt6B-3ln9A:
8.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
7 / 12 VAL A   2
ALA A  24
ARG A  72
ASN A  74
VAL A  79
ALA A  98
TYR A 113
None
None
None
None
None
None
GOL  A 137 (-4.8A)
0.89A 3qxvA-3ln9A:
19.5
3qxvA-3ln9A:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
6 / 12 VAL A   2
ALA A  24
ARG A  72
VAL A  79
ALA A  98
TYR A 113
None
None
None
None
None
GOL  A 137 (-4.8A)
0.92A 3qxvB-3ln9A:
19.4
3qxvB-3ln9A:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
6 / 11 VAL A   2
ALA A  24
ARG A  72
ASN A  74
VAL A  79
ALA A  98
None
0.85A 3qxvC-3ln9A:
19.7
3qxvC-3ln9A:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
5 / 12 ALA A  24
ARG A  72
VAL A  79
ALA A  98
TYR A 113
None
None
None
None
GOL  A 137 (-4.8A)
0.77A 3qxvD-3ln9A:
19.2
3qxvD-3ln9A:
67.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
5 / 12 ALA A  24
ARG A  72
VAL A  79
ALA A  98
TYR A 113
None
None
None
None
GOL  A 137 (-4.8A)
0.84A 3qxvE-3ln9A:
16.0
3qxvE-3ln9A:
67.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
4 / 7 HIS A  34
ILE A  51
VAL A  50
TYR A  59
None
1.32A 5kkzM-3ln9A:
0.8
5kkzO-3ln9A:
undetectable
5kkzM-3ln9A:
19.11
5kkzO-3ln9A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN4_A_SC2A1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)
3ln9 IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN B10

(Camelidae)
4 / 4 HIS A  34
GLY A  99
ARG A  32
THR A 106
None
None
GOL  A 139 ( 3.0A)
GOL  A 139 (-4.4A)
1.42A 5nn4A-3ln9A:
2.0
5nn4A-3ln9A:
9.89