SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lnb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		3 / 3 LEU A  29
LEU A 132
SER A 144
 None
FMT  A1002 ( 4.6A)
FMT  A1002 (-4.4A)
 0.52A 1tlmA-3lnbA:
undetectable		 1tlmA-3lnbA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 ARG A  65
ASP A  42
ILE A  48
GLU A  39
 None
 1.27A 2xrzA-3lnbA:
undetectable
2xrzB-3lnbA:
undetectable		 2xrzA-3lnbA:
23.92
2xrzB-3lnbA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  60
LEU A  56
ILE A 266
SER A  74
VAL A 201
 None
 1.17A 3aqiB-3lnbA:
undetectable		 3aqiB-3lnbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  72
ASN A  73
LEU A  75
LEU A  13
LEU A 225
 None
 1.22A 3d90B-3lnbA:
undetectable		 3d90B-3lnbA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 PHE A  38
CYH A  69
VAL A  94
PHE A 216
 COA  A1001 (-4.4A)
COA  A1001 (-2.6A)
COA  A1001 ( 4.7A)
COA  A1001 (-3.7A)
 0.38A 3ltwA-3lnbA:
30.7		 3ltwA-3lnbA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  60
LEU A  56
ILE A 266
SER A  74
VAL A 201
 None
 1.12A 3w1wA-3lnbA:
undetectable		 3w1wA-3lnbA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		3 / 3 LYS A 246
THR A 239
ILE A 221
 COA  A1001 (-2.6A)
COA  A1001 (-3.9A)
COA  A1001 ( 3.8A)
 0.81A 4e0fB-3lnbA:
undetectable		 4e0fB-3lnbA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 GLY A 125
GLY A  67
LEU A  72
GLN A 205
HIS A 108
 None
None
None
None
COA  A1001 ( 4.1A)
 1.14A 4l8fD-3lnbA:
undetectable		 4l8fD-3lnbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 8 ILE A  51
GLU A  71
GLN A 205
LEU A  68
 None
None
None
COA  A1001 ( 4.4A)
 0.86A 4mj8A-3lnbA:
undetectable		 4mj8A-3lnbA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 LEU A  80
MET A  32
ILE A 196
VAL A 201
 None
 0.80A 4ojbA-3lnbA:
undetectable		 4ojbA-3lnbA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 PHE A  38
ASP A 123
LEU A  72
HIS A 108
 COA  A1001 (-4.4A)
None
None
COA  A1001 ( 4.1A)
 1.25A 4paeA-3lnbA:
undetectable		 4paeA-3lnbA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 PHE A  79
LEU A  80
ALA A 124
MET A  32
 None
 0.92A 4rjdB-3lnbA:
undetectable		 4rjdB-3lnbA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 LEU A 260
ALA A 220
ASN A  40
ILE A 221
 None
None
None
COA  A1001 ( 3.8A)
 1.18A 4y03B-3lnbA:
undetectable		 4y03B-3lnbA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 ALA A  45
ARG A  65
ALA A 220
GLU A  39
 None
 1.42A 5a06C-3lnbA:
undetectable
5a06D-3lnbA:
undetectable		 5a06C-3lnbA:
22.40
5a06D-3lnbA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A 110
HIS A 108
GLY A  92
PHE A 137
ILE A 187
 None
COA  A1001 ( 4.1A)
None
None
None
 1.18A 5ih0A-3lnbA:
undetectable		 5ih0A-3lnbA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 8 PHE A 191
ARG A 150
ILE A 151
GLY A 139
 None
 0.92A 5nzxA-3lnbA:
undetectable		 5nzxA-3lnbA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A 111
LEU A  72
ASN A  73
PHE A   9
LEU A  25
 None
 1.01A 6dwnC-3lnbA:
undetectable		 6dwnC-3lnbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 VAL A 121
ASP A 106
ASN A  73
ILE A 196
TYR A  88
 None
 1.22A 6mxtA-3lnbA:
undetectable		 6mxtA-3lnbA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3lnb N-ACETYLTRANSFERASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ALA A 220
GLY A 219
GLY A  46
ASN A  40
 None
 0.80A 6nm4A-3lnbA:
undetectable		 6nm4A-3lnbA:
17.69