SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3lnc GUANYLATE KINASE
(Anaplasma
phagocytophilum) 		5 / 12 THR A  41
GLY A  84
GLU A  74
VAL A  38
VAL A  85
 None
5GP  A 300 (-3.3A)
5GP  A 300 (-2.9A)
None
5GP  A 300 (-4.1A)
 1.29A 1n2xA-3lncA:
undetectable		 1n2xA-3lncA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3lnc GUANYLATE KINASE
(Anaplasma
phagocytophilum) 		4 / 5 TYR A 165
VAL A  10
SER A 122
GLY A 108
 None
None
None
5GP  A 300 (-3.4A)
 1.45A 3v4tA-3lncA:
undetectable
3v4tD-3lncA:
undetectable		 3v4tA-3lncA:
19.91
3v4tD-3lncA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3lnc GUANYLATE KINASE
(Anaplasma
phagocytophilum) 		4 / 4 VAL A  94
GLY A   6
ARG A 194
VAL A 120
 None
 1.09A 5d4nA-3lncA:
undetectable
5d4nB-3lncA:
undetectable		 5d4nA-3lncA:
20.35
5d4nB-3lncA:
20.35