SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lnp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 HIS A  88
HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.85A 1a4lA-3lnpA:
20.7		 1a4lA-3lnpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.81A 1a4lB-3lnpA:
20.7		 1a4lB-3lnpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 LEU A 106
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 None
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 1.13A 1a4lB-3lnpA:
20.7		 1a4lB-3lnpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 LEU A 110
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 None
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.95A 1a4lB-3lnpA:
20.7		 1a4lB-3lnpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 HIS A  88
HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.86A 1a4lC-3lnpA:
20.6		 1a4lC-3lnpA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 6 HIS A  88
HIS A  90
HIS A 216
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-3.6A)
None
None
CA  A 471 (-2.7A)
 1.12A 1fweC-3lnpA:
18.7		 1fweC-3lnpA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 11 ALA A 147
GLY A 332
HIS A  90
GLY A 329
ILE A 300
 None
None
CA  A 471 (-3.6A)
None
None
 1.03A 1pg2A-3lnpA:
undetectable		 1pg2A-3lnpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		3 / 3 TRP A 115
THR A 220
TYR A 219
 None
 0.63A 2a3aA-3lnpA:
6.5		 2a3aA-3lnpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		3 / 3 TRP A 115
THR A 220
TYR A 219
 None
 0.57A 2a3aB-3lnpA:
6.9		 2a3aB-3lnpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		3 / 3 TRP A 115
THR A 220
TYR A 219
 None
 0.65A 2a3bA-3lnpA:
6.6		 2a3bA-3lnpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 GLY A 207
ILE A  55
GLY A  54
VAL A 430
ILE A 384
 None
 0.84A 2avsA-3lnpA:
undetectable		 2avsA-3lnpA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 11 LEU A 110
HIS A 216
HIS A 243
THR A 247
GLU A 246
 None
None
CA  A 471 (-4.7A)
None
None
 1.37A 2dttD-3lnpA:
undetectable
2dttE-3lnpA:
undetectable		 2dttD-3lnpA:
13.82
2dttE-3lnpA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 HIS A 243
ASP A 175
THR A 220
HIS A  88
 CA  A 471 (-4.7A)
None
None
CA  A 471 (-3.6A)
 1.50A 2dysA-3lnpA:
undetectable
2dysC-3lnpA:
undetectable		 2dysA-3lnpA:
22.14
2dysC-3lnpA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 HIS A 243
ASP A 175
THR A 220
HIS A  88
 CA  A 471 (-4.7A)
None
None
CA  A 471 (-3.6A)
 1.48A 2dysN-3lnpA:
undetectable
2dysP-3lnpA:
undetectable		 2dysN-3lnpA:
22.14
2dysP-3lnpA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 ASN A 336
ASN A 306
VAL A 114
SER A 311
HIS A 280
 CA  A 472 (-2.9A)
None
None
None
None
 1.36A 2gl0A-3lnpA:
undetectable
2gl0C-3lnpA:
undetectable		 2gl0A-3lnpA:
16.09
2gl0C-3lnpA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 PRO A 172
HIS A 216
ASP A 175
TYR A 187
 None
 1.40A 2lh8A-3lnpA:
undetectable		 2lh8A-3lnpA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
GLU A 246
HIS A 280
SER A 305
ASP A 331
 CA  A 471 (-3.6A)
None
None
None
CA  A 471 (-2.7A)
 0.56A 2pgfA-3lnpA:
21.8		 2pgfA-3lnpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A 243
GLU A 246
HIS A 280
SER A 305
ASP A 331
 CA  A 471 (-4.7A)
None
None
None
CA  A 471 (-2.7A)
 0.68A 2pgfA-3lnpA:
21.8		 2pgfA-3lnpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 HIS A  88
HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.80A 2pgrA-3lnpA:
21.9		 2pgrA-3lnpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 8 ASP A 331
HIS A 280
SER A 311
LEU A 309
 CA  A 471 (-2.7A)
None
None
None
 1.03A 2q0iA-3lnpA:
undetectable		 2q0iA-3lnpA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 11 ASP A 331
HIS A  88
HIS A 280
SER A 311
LEU A 309
 CA  A 471 (-2.7A)
CA  A 471 (-3.6A)
None
None
None
 1.06A 2q0jB-3lnpA:
undetectable		 2q0jB-3lnpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 11 HIS A  88
HIS A 216
HIS A 280
SER A 311
LEU A 309
 CA  A 471 (-3.6A)
None
None
None
None
 1.29A 2q0jB-3lnpA:
undetectable		 2q0jB-3lnpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 PHE A 249
LEU A 106
MET A 107
HIS A 216
VAL A 114
 None
 1.32A 2qd4B-3lnpA:
undetectable		 2qd4B-3lnpA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 GLN A 210
ALA A 378
ALA A 376
THR A 385
 None
 0.96A 2xfhA-3lnpA:
undetectable		 2xfhA-3lnpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 LEU A 133
ALA A 136
ILE A 165
ILE A 450
ALA A 453
 None
 1.21A 3axtA-3lnpA:
2.6		 3axtA-3lnpA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 GLY A 207
ILE A  55
GLY A  54
VAL A 430
ILE A 384
 None
 0.87A 3cyxB-3lnpA:
undetectable		 3cyxB-3lnpA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		3 / 3 MET A 370
CYH A 314
PRO A 303
 None
 1.20A 3h52C-3lnpA:
undetectable		 3h52C-3lnpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 9 PHE A 146
ALA A 163
THR A 443
VAL A 430
VAL A 428
 None
 1.10A 3me6C-3lnpA:
undetectable		 3me6C-3lnpA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 9 PHE A 146
ALA A 163
THR A 443
VAL A 430
VAL A 428
 None
 1.16A 3me6D-3lnpA:
undetectable		 3me6D-3lnpA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 HIS A  90
ASP A 103
ASP A 331
ASN A 337
 CA  A 471 (-3.6A)
None
CA  A 471 (-2.7A)
None
 0.96A 3vywA-3lnpA:
undetectable		 3vywA-3lnpA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 7 SER A 252
THR A 257
THR A 247
PHE A 249
 None
 0.75A 4ac9C-3lnpA:
2.2		 4ac9C-3lnpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 7 SER A 252
THR A 257
THR A 247
PHE A 249
 None
 0.73A 4acaC-3lnpA:
2.3		 4acaC-3lnpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 SER A 252
THR A 257
THR A 247
PHE A 249
 None
 0.72A 4acbC-3lnpA:
2.3		 4acbC-3lnpA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 HIS A 243
GLU A 246
GLU A 250
HIS A 280
SER A 305
ASP A 331
 CA  A 471 (-4.7A)
None
None
None
None
CA  A 471 (-2.7A)
 0.76A 4aqlA-3lnpA:
43.9		 4aqlA-3lnpA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 LEU A 106
HIS A 243
GLU A 246
GLU A 250
HIS A 280
ASP A 331
 None
CA  A 471 (-4.7A)
None
None
None
CA  A 471 (-2.7A)
 1.41A 4aqlA-3lnpA:
43.9		 4aqlA-3lnpA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		6 / 12 LEU A 110
GLU A 246
GLU A 250
HIS A 280
SER A 305
ASP A 331
 None
None
None
None
None
CA  A 471 (-2.7A)
 0.82A 4aqlA-3lnpA:
43.9		 4aqlA-3lnpA:
26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 11 SER A 141
THR A 143
GLU A 132
ALA A 163
THR A 443
 None
 1.06A 4e0fA-3lnpA:
undetectable		 4e0fA-3lnpA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 5 HIS A 245
THR A 247
GLU A 250
HIS A 216
 None
 1.39A 4hvcB-3lnpA:
undetectable		 4hvcB-3lnpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 ALA A 159
ALA A 162
ALA A 163
THR A 443
LEU A 449
 None
 1.07A 4j6dA-3lnpA:
undetectable		 4j6dA-3lnpA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 ALA A 159
ALA A 162
ALA A 163
THR A 443
LEU A 449
 None
 1.09A 4j6dB-3lnpA:
undetectable		 4j6dB-3lnpA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 SER A 141
GLY A  89
ASP A 148
GLY A 332
 None
 0.93A 4koeA-3lnpA:
undetectable
4koeB-3lnpA:
1.4
4koeC-3lnpA:
undetectable		 4koeA-3lnpA:
23.94
4koeB-3lnpA:
23.94
4koeC-3lnpA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 7 SER A 141
GLY A  89
ASP A 148
GLY A 332
 None
 0.91A 4koeA-3lnpA:
undetectable
4koeB-3lnpA:
undetectable
4koeD-3lnpA:
undetectable		 4koeA-3lnpA:
23.94
4koeB-3lnpA:
23.94
4koeD-3lnpA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 VAL A 168
LEU A 208
ARG A 166
THR A 385
ILE A 384
 None
 0.93A 4o5fA-3lnpA:
undetectable
4o5fB-3lnpA:
undetectable		 4o5fA-3lnpA:
23.57
4o5fB-3lnpA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 VAL A 168
LEU A 208
ARG A 166
THR A 385
ILE A 384
 None
 0.92A 4o5fA-3lnpA:
undetectable
4o5fB-3lnpA:
undetectable		 4o5fA-3lnpA:
23.57
4o5fB-3lnpA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
LEU A 309
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.96A 4r88B-3lnpA:
31.1		 4r88B-3lnpA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
LEU A 309
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.96A 4r88C-3lnpA:
30.5		 4r88C-3lnpA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
LEU A 309
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.98A 4r88F-3lnpA:
30.4		 4r88F-3lnpA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 ILE A 165
ALA A 378
ALA A 147
ASP A 148
PHE A 170
 None
 0.75A 4v01A-3lnpA:
undetectable		 4v01A-3lnpA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 GLY A  89
ASP A 148
GLY A 332
SER A 141
 None
 0.86A 4z53A-3lnpA:
undetectable
4z53B-3lnpA:
undetectable		 4z53A-3lnpA:
21.34
4z53B-3lnpA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 7 GLY A  89
ASP A 148
GLY A 332
SER A 141
 None
 0.84A 4z53A-3lnpA:
undetectable
4z53B-3lnpA:
undetectable		 4z53A-3lnpA:
21.34
4z53B-3lnpA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 VAL A 168
LEU A 208
ARG A 166
THR A 385
ILE A 384
 None
 0.94A 5b8hA-3lnpA:
undetectable
5b8hB-3lnpA:
undetectable		 5b8hA-3lnpA:
21.00
5b8hB-3lnpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 VAL A 168
LEU A 208
ARG A 166
THR A 385
ILE A 384
 None
 0.94A 5b8hA-3lnpA:
undetectable
5b8hB-3lnpA:
undetectable		 5b8hA-3lnpA:
21.00
5b8hB-3lnpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 6 SER A 141
GLY A  89
ASP A 148
GLY A 332
 None
 0.86A 5cdnA-3lnpA:
undetectable
5cdnB-3lnpA:
undetectable		 5cdnA-3lnpA:
22.45
5cdnB-3lnpA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		3 / 3 GLU A 118
TRP A 109
HIS A  90
 None
None
CA  A 471 (-3.6A)
 0.82A 5xipA-3lnpA:
undetectable		 5xipA-3lnpA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.79A 6n91A-3lnpA:
21.4		 6n91A-3lnpA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 LEU A 106
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 None
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 1.15A 6n91A-3lnpA:
21.4		 6n91A-3lnpA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 4 HIS A  90
LEU A 174
TYR A 187
GLY A 214
 CA  A 471 (-3.6A)
None
None
None
 1.18A 6n91A-3lnpA:
21.0		 6n91A-3lnpA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 HIS A  90
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 CA  A 471 (-3.6A)
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 0.79A 6n91B-3lnpA:
21.3		 6n91B-3lnpA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		5 / 12 LEU A 106
HIS A 243
GLU A 246
HIS A 280
ASP A 331
 None
CA  A 471 (-4.7A)
None
None
CA  A 471 (-2.7A)
 1.19A 6n91B-3lnpA:
21.3		 6n91B-3lnpA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465
(Oleispira
antarctica) 		4 / 4 HIS A  90
LEU A 174
TYR A 187
GLY A 214
 CA  A 471 (-3.6A)
None
None
None
 1.19A 6n91B-3lnpA:
21.1		 6n91B-3lnpA:
10.52