SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 11 LEU A 216
LEU A 193
LEU A 189
ILE A 167
ALA A 168
 None
 1.02A 1ha2A-3lntA:
undetectable		 1ha2A-3lntA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 193
LEU A 189
ILE A 179
ILE A 167
ALA A 168
 None
 1.04A 2bxqA-3lntA:
undetectable		 2bxqA-3lntA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 11 SER A  82
LEU A   6
LEU A   4
SER A 166
LEU A 193
 None
 1.09A 2xn5A-3lntA:
undetectable		 2xn5A-3lntA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 ILE A 179
ALA A 181
ARG A 158
LEU A  85
VAL A 171
 None
 1.04A 3dzuA-3lntA:
undetectable		 3dzuA-3lntA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 ILE A 179
ALA A 181
ARG A 158
LEU A  85
VAL A 171
 None
 1.08A 3dzyA-3lntA:
undetectable		 3dzyA-3lntA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  61
GLY A  22
SER A  56
LEU A  85
SER A 185
 None
MLI  A 990 (-3.6A)
None
None
None
 0.91A 3gyqA-3lntA:
undetectable
3gyqB-3lntA:
undetectable		 3gyqA-3lntA:
22.82
3gyqB-3lntA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		4 / 5 VAL A 159
LEU A 162
ILE A 179
ALA A 181
 None
 0.85A 3n8yB-3lntA:
undetectable		 3n8yB-3lntA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		4 / 5 TYR A  90
THR A  21
ARG A 130
LEU A 124
 MLI  A 990 (-4.6A)
MLI  A 990 (-3.8A)
None
None
 1.46A 3qelC-3lntA:
3.9		 3qelC-3lntA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		4 / 4 GLU A  30
GLY A  32
HIS A  67
ARG A  37
 None
None
EDO  A 251 (-3.5A)
None
 1.01A 4r82A-3lntA:
undetectable
4r82B-3lntA:
undetectable		 4r82A-3lntA:
24.90
4r82B-3lntA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		4 / 6 TYR A  48
GLU A 215
TYR A 226
LEU A 212
 None
 1.17A 4twdB-3lntA:
undetectable
4twdC-3lntA:
undetectable		 4twdB-3lntA:
21.20
4twdC-3lntA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 THR A  55
ALA A 181
LEU A 186
LEU A 189
LEU A 178
 None
 1.26A 4xi3D-3lntA:
undetectable		 4xi3D-3lntA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		4 / 8 TYR A 214
ASP A 194
ILE A 223
TYR A 226
 None
 0.88A 4xjeA-3lntA:
undetectable		 4xjeA-3lntA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 216
LEU A 193
LEU A 189
ILE A 167
ALA A 168
 None
 1.15A 5v0vA-3lntA:
undetectable		 5v0vA-3lntA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE
(Burkholderia
pseudomallei) 		3 / 3 ARG A  19
PHE A  20
GLY A  95
 None
 0.69A 6fgdA-3lntA:
undetectable		 6fgdA-3lntA:
21.24