SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3lod PUTATIVE ACYL-COA
N-ACYLTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  61
ALA A  59
TYR A   2
SER A  54
ILE A  80
 None
 0.98A 1nt2A-3lodA:
undetectable		 1nt2A-3lodA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 3lod PUTATIVE ACYL-COA
N-ACYLTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  63
ILE A  52
TYR A   2
ALA A   0
GLN A  87
 None
 1.13A 1oltA-3lodA:
undetectable		 1oltA-3lodA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3lod PUTATIVE ACYL-COA
N-ACYLTRANSFERASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A   4
ILE A  52
VAL A  60
LEU A 123
LEU A  97
 None
 1.09A 3em0B-3lodA:
undetectable		 3em0B-3lodA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3lod PUTATIVE ACYL-COA
N-ACYLTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 4 ALA A  16
ALA A  19
ALA A  20
ALA A  23
 None
 0.12A 4oaeA-3lodA:
15.7		 4oaeA-3lodA:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3lod PUTATIVE ACYL-COA
N-ACYLTRANSFERASE
(Klebsiella
pneumoniae) 		4 / 8 ILE A  18
LEU A  93
ILE A  52
LEU A  39
 None
 1.01A 5ieoA-3lodA:
undetectable		 5ieoA-3lodA:
19.64