SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3loi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		3 / 3 PHE A 145
VAL A  71
GLU A  75
 None
 0.84A 4fvqA-3loiA:
undetectable		 4fvqA-3loiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		4 / 6 ARG A 166
GLY A  63
VAL A 126
HIS A  88
 None
 0.95A 4oltA-3loiA:
undetectable		 4oltA-3loiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		4 / 6 ARG A 166
GLY A  63
VAL A 126
HIS A  88
 None
 0.98A 4oltB-3loiA:
undetectable		 4oltB-3loiA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		5 / 12 GLY A 128
GLU A  11
VAL A  12
LEU A  15
ILE A  16
 None
 0.92A 6ectA-3loiA:
undetectable		 6ectA-3loiA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		5 / 12 LEU A  81
GLU A  11
VAL A  12
LEU A  15
ILE A  16
 None
 0.99A 6ecxA-3loiA:
undetectable		 6ecxA-3loiA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		5 / 12 LEU A  81
GLY A 128
GLU A  11
VAL A  12
ILE A  16
 None
 1.02A 6ecxA-3loiA:
undetectable		 6ecxA-3loiA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3loi PUTATIVE
UNCHARACTERIZED
PROTEIN
(Branchiostoma
belcheri) 		4 / 6 GLY A 139
THR A  54
ILE A  56
PHE A  31
 None
 0.76A 6f8cA-3loiA:
undetectable		 6f8cA-3loiA:
17.34