SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 8 LEU A  46
HIS A  47
LEU A  28
LEU A  32
 None
 0.76A 1e7cA-3lomA:
2.6		 1e7cA-3lomA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
ARG A 105
LYS A 192
THR A 193
 None
 0.93A 1rqjA-3lomA:
33.5		 1rqjA-3lomA:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		6 / 11 SER A  90
LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.92A 1rqjA-3lomA:
33.5		 1rqjA-3lomA:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		6 / 11 SER A  90
LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.93A 1rqjB-3lomA:
33.5		 1rqjB-3lomA:
38.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.44A 1yq7A-3lomA:
25.1		 1yq7A-3lomA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.91A 1yq7A-3lomA:
25.1		 1yq7A-3lomA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.14A 1yq7A-3lomA:
25.1		 1yq7A-3lomA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 5 LEU A 135
GLY A 160
ALA A 131
ILE A 132
 None
 0.84A 2aohB-3lomA:
undetectable		 2aohB-3lomA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 9 ASP A 100
ARG A 105
GLN A 168
THR A 193
GLN A 231
 None
 1.16A 2e91B-3lomA:
19.6		 2e91B-3lomA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.79A 2f94F-3lomA:
25.8		 2f94F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 0.89A 2f94F-3lomA:
25.8		 2f94F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 9 LEU A  91
ARG A 105
GLN A 168
LYS A 192
THR A 193
 None
 1.13A 2o1oA-3lomA:
25.0		 2o1oA-3lomA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 9 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.43A 2o1oA-3lomA:
25.0		 2o1oA-3lomA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 9 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.97A 2o1oA-3lomA:
25.0		 2o1oA-3lomA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		3 / 3 LEU A  28
TYR A  27
GLN A  30
 None
 0.67A 2wekA-3lomA:
undetectable		 2wekA-3lomA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.40A 3n45F-3lomA:
25.8		 3n45F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 1.03A 3n45F-3lomA:
25.8		 3n45F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.11A 3n45F-3lomA:
25.8		 3n45F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.38A 3n46F-3lomA:
25.9		 3n46F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 1.07A 3n46F-3lomA:
25.9		 3n46F-3lomA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 7 ILE A 296
LEU A 295
LYS A 224
GLY A 223
 None
 1.03A 4hbfA-3lomA:
undetectable		 4hbfA-3lomA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 7 ILE A 296
LEU A 295
LYS A 224
GLY A 223
 None
 1.05A 4hc3A-3lomA:
undetectable		 4hc3A-3lomA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.41A 4kq5A-3lomA:
25.0		 4kq5A-3lomA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 1.01A 4kq5A-3lomA:
25.0		 4kq5A-3lomA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.39A 4kqsA-3lomA:
25.9		 4kqsA-3lomA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.96A 4kqsA-3lomA:
25.9		 4kqsA-3lomA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.09A 4kqsA-3lomA:
25.9		 4kqsA-3lomA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.20A 4ng6A-3lomA:
25.7		 4ng6A-3lomA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.76A 4ng6A-3lomA:
25.7		 4ng6A-3lomA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 0.89A 4ng6A-3lomA:
25.7		 4ng6A-3lomA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.38A 4nuaA-3lomA:
25.9		 4nuaA-3lomA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.95A 4nuaA-3lomA:
25.9		 4nuaA-3lomA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.39A 4p0wA-3lomA:
26.0		 4p0wA-3lomA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 1.02A 4p0wA-3lomA:
26.0		 4p0wA-3lomA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 11 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.08A 4p0wA-3lomA:
26.0		 4p0wA-3lomA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ARG A 105
GLN A 168
THR A 193
GLN A 231
 None
 0.96A 4rxdA-3lomA:
24.5		 4rxdA-3lomA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
THR A 193
GLN A 231
 None
 0.85A 4rxdA-3lomA:
24.5		 4rxdA-3lomA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ARG A 105
GLN A 168
THR A 193
GLN A 231
 None
 0.94A 4rxdB-3lomA:
24.8		 4rxdB-3lomA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
THR A 193
GLN A 231
 None
 0.84A 4rxdB-3lomA:
24.8		 4rxdB-3lomA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ARG A 105
GLN A 168
THR A 193
GLN A 231
 None
 0.94A 4rxdC-3lomA:
24.8		 4rxdC-3lomA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 10 LEU A  91
ASP A 100
ARG A 105
THR A 193
GLN A 231
 None
 0.85A 4rxdC-3lomA:
24.8		 4rxdC-3lomA:
24.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		6 / 8 SER A  90
LEU A  91
ASP A 100
ARG A 105
MET A 164
GLN A 168
 None
 0.62A 4umjA-3lomA:
33.2		 4umjA-3lomA:
38.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1298_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 4 ILE A 197
PHE A 230
GLN A 231
ASP A 234
 None
 1.06A 4umjA-3lomA:
33.2		 4umjA-3lomA:
38.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 9 LEU A  91
ASP A  94
ASP A 100
GLN A 168
THR A 193
 None
 1.24A 4umjB-3lomA:
33.5		 4umjB-3lomA:
38.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		7 / 9 SER A  90
LEU A  91
ASP A 100
ARG A 105
MET A 164
GLN A 168
THR A 193
 None
 0.68A 4umjB-3lomA:
33.5		 4umjB-3lomA:
38.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.96A 5cg5A-3lomA:
25.6		 5cg5A-3lomA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.08A 5cg5A-3lomA:
25.6		 5cg5A-3lomA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
ARG A 105
GLN A 168
THR A 193
 None
 0.96A 5cg6A-3lomA:
26.0		 5cg6A-3lomA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 12 LEU A  91
ASP A 100
GLN A 168
THR A 193
GLN A 231
 None
 1.10A 5cg6A-3lomA:
26.0		 5cg6A-3lomA:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 7 GLN A  73
LEU A  76
ALA A  82
LEU A  85
 None
 1.06A 5nwvA-3lomA:
undetectable		 5nwvA-3lomA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 6 ILE A 274
LEU A 237
ARG A 305
SER A 306
 None
 1.30A 6f6jA-3lomA:
undetectable		 6f6jA-3lomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 7 ASP A 100
ARG A 105
GLN A 168
GLN A 231
 None
 0.90A 6g31A-3lomA:
23.2		 6g31A-3lomA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 6 ASP A 100
ARG A 105
GLN A 168
GLN A 231
 None
 0.91A 6g31B-3lomA:
23.7		 6g31B-3lomA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 7 LEU A  91
ASP A 100
ARG A 105
GLN A 168
GLN A 231
 None
 0.94A 6g31D-3lomA:
22.6		 6g31D-3lomA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		5 / 6 LEU A  91
ASP A 100
ARG A 105
GLN A 168
GLN A 231
 None
 0.95A 6g31J-3lomA:
23.6		 6g31J-3lomA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3lom GERANYLTRANSTRANSFER
ASE
(Legionella
pneumophila) 		4 / 5 ARG A 186
LEU A 228
GLN A 231
PHE A 230
 None
 1.43A 6nmpP-3lomA:
3.2
6nmpW-3lomA:
undetectable		 6nmpP-3lomA:
21.71
6nmpW-3lomA:
11.18