SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3loq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 145
TYR A  17
ALA A  74
GLY A  75
PHE A 136
 None
 1.43A 1l5rA-3loqA:
2.2		 1l5rA-3loqA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 11 GLU A  27
PHE A  -4
GLY A  25
ARG A 161
LEU A  -6
 None
 1.40A 1mjqA-3loqA:
undetectable
1mjqB-3loqA:
undetectable		 1mjqA-3loqA:
20.55
1mjqB-3loqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 TYR A 134
PHE A 102
ALA A   0
ALA A 162
ALA A 166
 None
 1.17A 2x2nA-3loqA:
undetectable		 2x2nA-3loqA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.35A 3fhjA-3loqA:
2.4		 3fhjA-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.35A 3fhjB-3loqA:
3.2		 3fhjB-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fhjC-3loqA:
3.2		 3fhjC-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.35A 3fhjD-3loqA:
3.4		 3fhjD-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fhjE-3loqA:
undetectable		 3fhjE-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fhjF-3loqA:
2.7		 3fhjF-3loqA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fi0A-3loqA:
2.8		 3fi0A-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fi0C-3loqA:
3.4		 3fi0C-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.37A 3fi0D-3loqA:
3.5		 3fi0D-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		6 / 9 GLY A 124
VAL A 241
HIS A 127
ASP A 128
ILE A  94
VAL A 133
 None
 1.47A 3fi0F-3loqA:
3.5		 3fi0F-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.35A 3fi0H-3loqA:
3.4		 3fi0H-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.37A 3fi0J-3loqA:
undetectable		 3fi0J-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.37A 3fi0K-3loqA:
3.3		 3fi0K-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.35A 3fi0L-3loqA:
3.4		 3fi0L-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.36A 3fi0M-3loqA:
3.3		 3fi0M-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
ASP A 128
ILE A  94
VAL A 133
 None
 1.33A 3fi0N-3loqA:
3.4		 3fi0N-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		6 / 9 GLY A 124
VAL A 241
HIS A 127
ASP A 128
ILE A  94
VAL A 133
 None
 1.44A 3fi0R-3loqA:
3.5		 3fi0R-3loqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 PHE A  -4
PHE A 262
TYR A 134
VAL A 169
 None
 1.10A 3lb3A-3loqA:
undetectable		 3lb3A-3loqA:
18.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 154
SER A 156
ARG A 236
 ACT  A 276 ( 3.6A)
ACT  A 277 ( 3.8A)
ACT  A 277 (-4.4A)
 0.00A 3loqA-3loqA:
49.7		 3loqA-3loqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 SER A 107
GLY A 109
SER A 120
 CL  A 273 (-2.9A)
CL  A 273 ( 3.7A)
AMP  A 271 (-2.6A)
 0.53A 3loqA-3loqA:
49.7		 3loqA-3loqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 SER A 235
GLY A 237
SER A 248
 ACT  A 279 ( 3.2A)
ACT  A 278 (-3.4A)
ACT  A 279 ( 4.2A)
 0.00A 3loqA-3loqA:
49.7		 3loqA-3loqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		4 / 4 SER A 235
SER A 248
THR A 249
SER A 250
 ACT  A 279 ( 3.2A)
ACT  A 279 ( 4.2A)
CL  A 274 ( 3.4A)
ACT  A 279 (-3.0A)
 0.02A 3loqA-3loqA:
49.7		 3loqA-3loqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 175
GLY A 174
VAL A  24
GLU A 205
ILE A 204
 None
 1.27A 3owxA-3loqA:
undetectable		 3owxA-3loqA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 ASN A  36
ILE A  94
ASP A 128
GLY A 124
SER A 120
 None
None
None
None
AMP  A 271 (-2.6A)
 1.30A 4djfA-3loqA:
undetectable		 4djfA-3loqA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 124
VAL A 241
HIS A 127
ASP A 128
ILE A  94
 None
 1.40A 5v0iB-3loqA:
2.8		 5v0iB-3loqA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 VAL A  26
PHE A  21
PHE A 102
ILE A 231
PHE A 232
 None
 1.42A 6becA-3loqA:
undetectable
6becB-3loqA:
undetectable
6becC-3loqA:
undetectable		 6becA-3loqA:
21.51
6becB-3loqA:
21.51
6becC-3loqA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3loq UNIVERSAL STRESS
PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 169
THR A 173
PHE A 232
PHE A  21
VAL A  26
 None
 1.45A 6drxA-3loqA:
undetectable		 6drxA-3loqA:
21.00