SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lp5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		4 / 6 TYR A 118
TRP A 111
VAL A   9
ILE A  64
 None
 1.21A 1j96A-3lp5A:
undetectable		 1j96A-3lp5A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 MET A 150
GLU A 153
LEU A 154
GLU A 116
 None
 1.03A 1linA-3lp5A:
undetectable		 1linA-3lp5A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 11 THR A 132
SER A 135
LEU A  83
PHE A  66
VAL A   9
 None
 1.38A 1q23J-3lp5A:
undetectable		 1q23J-3lp5A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 103
LEU A 109
VAL A  63
LEU A 102
GLY A  65
 None
 1.15A 2f8lA-3lp5A:
undetectable		 2f8lA-3lp5A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		4 / 7 VAL A 187
ALA A 171
PHE A 151
THR A 112
 None
 0.86A 2q6oA-3lp5A:
2.6		 2q6oA-3lp5A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 9 VAL A 187
GLY A 190
LYS A 191
THR A 132
GLY A 108
 None
 1.41A 3bjwG-3lp5A:
0.2		 3bjwG-3lp5A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 GLY A 108
GLY A 107
GLY A  11
SER A 135
 None
 0.60A 3d41A-3lp5A:
undetectable		 3d41A-3lp5A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 SER A  15
GLN A  16
PHE A  19
 None
 0.75A 3g4lC-3lp5A:
undetectable		 3g4lC-3lp5A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 LEU A  83
ALA A  80
LEU A 115
ILE A 193
LEU A 161
 None
 1.15A 4j24D-3lp5A:
undetectable		 4j24D-3lp5A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 12 ILE A  64
GLY A  65
ASN A  69
VAL A  41
ILE A  47
 None
 1.15A 4rvgA-3lp5A:
2.2		 4rvgA-3lp5A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		5 / 10 VAL A  63
ILE A  64
LEU A  83
PHE A  66
ILE A 222
 None
 1.30A 5hw8C-3lp5A:
undetectable
5hw8H-3lp5A:
undetectable		 5hw8C-3lp5A:
18.29
5hw8H-3lp5A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		3 / 3 GLN A  42
THR A  46
ASP A  44
 None
 0.94A 5k9dA-3lp5A:
undetectable		 5k9dA-3lp5A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 3lp5 PUTATIVE CELL
SURFACE HYDROLASE
(Lactobacillus
plantarum) 		4 / 8 PHE A 201
VAL A 187
SER A 135
TYR A 137
 None
 1.13A 6huoC-3lp5A:
undetectable
6huoD-3lp5A:
undetectable		 6huoC-3lp5A:
18.55
6huoD-3lp5A:
19.21