SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3lp9 LS-24
(Lathyrus
sativus) 		3 / 3 PHE A  82
TYR A  62
LEU A  85
 None
 0.80A 3keeB-3lp9A:
undetectable		 3keeB-3lp9A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3lp9 LS-24
(Lathyrus
sativus) 		5 / 12 SER A  67
PHE A  10
ASP A  87
ASP A  69
ILE A  77
 CL  A 314 (-3.9A)
None
None
NA  A 318 (-3.3A)
None
 1.37A 4ktvA-3lp9A:
undetectable
4ktvB-3lp9A:
undetectable		 4ktvA-3lp9A:
20.40
4ktvB-3lp9A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3lp9 LS-24
(Lathyrus
sativus) 		5 / 9 VAL A 186
ILE A  77
ALA A  75
THR A  70
VAL A 132
 None
 1.31A 4oqrA-3lp9A:
undetectable		 4oqrA-3lp9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3lp9 LS-24
(Lathyrus
sativus) 		5 / 12 GLY A 100
LEU A 134
CYH A  83
ILE A 104
ASP A 106
 None
 0.85A 6bxmA-3lp9A:
undetectable		 6bxmA-3lp9A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3lp9 LS-24
(Lathyrus
sativus) 		5 / 12 ASP A  69
ILE A  77
SER A  67
PHE A  10
ASP A  87
 NA  A 318 (-3.3A)
None
CL  A 314 (-3.9A)
None
None
 1.47A 6fbpA-3lp9A:
undetectable
6fbpB-3lp9A:
undetectable		 6fbpA-3lp9A:
15.45
6fbpB-3lp9A:
15.45