SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 ILE A 345
LEU A 342
TYR A 316
ILE A 335
PHE A 226
 None
 1.17A 1fmlB-3lq1A:
undetectable		 1fmlB-3lq1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 TRP A 359
VAL A 268
TRP A 249
 None
 1.47A 1gmkC-3lq1A:
undetectable
1gmkD-3lq1A:
undetectable		 1gmkC-3lq1A:
5.20
1gmkD-3lq1A:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 LYS A 233
ASP A 208
ASP A 338
 None
 0.87A 2br4D-3lq1A:
3.3		 2br4D-3lq1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 9 GLU A 267
ILE A 251
ALA A 253
VAL A 228
PHE A 294
 None
 1.30A 2drdA-3lq1A:
undetectable		 2drdA-3lq1A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 ASP A 274
ASP A 254
ASP A 413
 None
 0.72A 2igtA-3lq1A:
3.3		 2igtA-3lq1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 ASP A 274
ASP A 254
ASP A 413
 None
 0.71A 2igtB-3lq1A:
2.8		 2igtB-3lq1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 5 GLY A  81
HIS A 125
ASP A 133
ASP A 107
 None
 0.95A 2oxtB-3lq1A:
2.2		 2oxtB-3lq1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 LEU A 256
PRO A 230
ARG A 412
 None
 0.66A 2qd4B-3lq1A:
3.3		 2qd4B-3lq1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 LYS A 222
ARG A 314
VAL A 290
 None
 0.97A 2r2vC-3lq1A:
undetectable
2r2vD-3lq1A:
undetectable		 2r2vC-3lq1A:
7.31
2r2vD-3lq1A:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 LEU A 171
MET A 137
MET A 121
 None
 0.71A 2vavF-3lq1A:
undetectable		 2vavF-3lq1A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 6 LEU A 469
ILE A 481
ILE A 425
LEU A 428
 None
 0.74A 2xkwB-3lq1A:
undetectable		 2xkwB-3lq1A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		6 / 12 LEU A 469
GLY A 468
VAL A  54
ASP A 465
LEU A 444
LEU A 479
 None
 1.36A 3cjtC-3lq1A:
2.7		 3cjtC-3lq1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 LEU A 469
GLY A 468
VAL A  54
LEU A 444
LEU A 479
 None
 1.34A 3cjtK-3lq1A:
undetectable		 3cjtK-3lq1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 ILE A 328
LEU A 307
LEU A 310
VAL A 291
PRO A 327
 None
 1.17A 3dcjA-3lq1A:
2.1
3dcjB-3lq1A:
2.5		 3dcjA-3lq1A:
17.59
3dcjB-3lq1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 9 ILE A 160
GLY A 167
ILE A  99
VAL A  24
ILE A 102
 None
 1.25A 3ekyB-3lq1A:
undetectable		 3ekyB-3lq1A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		6 / 12 PHE A 404
ILE A 405
GLY A 406
ILE A 436
ALA A 429
VAL A 414
 None
 1.29A 3fpjA-3lq1A:
undetectable		 3fpjA-3lq1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 GLY A  32
LEU A 179
LEU A  38
GLY A  81
SER A  80
 None
 1.03A 3g2oA-3lq1A:
undetectable		 3g2oA-3lq1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 GLY A  32
LEU A 179
LEU A  38
GLY A  81
SER A  80
 None
 1.02A 3g2oB-3lq1A:
undetectable		 3g2oB-3lq1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 VAL A 439
PHE A 404
SER A 408
ILE A 411
VAL A 484
 None
 1.21A 3iw1A-3lq1A:
undetectable		 3iw1A-3lq1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 ILE A 483
SER A 461
SER A 408
ASN A 486
 None
 0.88A 3lslA-3lq1A:
1.0
3lslD-3lq1A:
undetectable		 3lslA-3lq1A:
19.48
3lslD-3lq1A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 SER A 408
ASN A 486
ILE A 483
SER A 461
 None
 0.93A 3lslA-3lq1A:
1.0
3lslD-3lq1A:
undetectable		 3lslA-3lq1A:
19.48
3lslD-3lq1A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 6 ALA A 429
ILE A 411
LEU A 256
GLU A  93
 None
 0.83A 3r9sA-3lq1A:
undetectable		 3r9sA-3lq1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 6 ALA A 429
ILE A 411
LEU A 256
GLU A  93
 None
 0.81A 3r9sC-3lq1A:
undetectable		 3r9sC-3lq1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 PHE A 454
ILE A 405
LEU A 397
PHE A 418
 None
 1.02A 3rqwI-3lq1A:
undetectable
3rqwJ-3lq1A:
undetectable		 3rqwI-3lq1A:
20.24
3rqwJ-3lq1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 VAL A  75
LEU A 104
LEU A  77
ILE A  16
 None
 0.92A 3u5kC-3lq1A:
undetectable		 3u5kC-3lq1A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 5 VAL A  75
LEU A 104
LEU A  77
ILE A  16
 None
 0.81A 4a9jA-3lq1A:
undetectable		 4a9jA-3lq1A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 5 VAL A  75
LEU A 104
LEU A  77
ILE A  16
 None
 0.82A 4a9jB-3lq1A:
undetectable		 4a9jB-3lq1A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 5 VAL A  75
LEU A 104
LEU A  77
ILE A  16
 None
 0.93A 4a9jC-3lq1A:
undetectable		 4a9jC-3lq1A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 GLY A 445
GLY A  65
VAL A 449
VAL A  74
 None
 0.89A 4c5nC-3lq1A:
undetectable		 4c5nC-3lq1A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		3 / 3 ASP A 271
ARG A 371
ASP A 274
 None
 0.78A 4fp9A-3lq1A:
2.2		 4fp9A-3lq1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 11 PRO A 174
ASP A 136
PHE A 134
ASP A 107
ASP A 122
 None
 1.50A 4ktvC-3lq1A:
undetectable
4ktvD-3lq1A:
undetectable		 4ktvC-3lq1A:
23.28
4ktvD-3lq1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 11 ASP A  53
VAL A 448
ALA A 446
SER A 441
SER A 442
 None
 1.18A 4mmaA-3lq1A:
undetectable		 4mmaA-3lq1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 LEU A  64
PHE A  61
ILE A  99
GLY A 432
ALA A 433
 None
 1.05A 4nkvA-3lq1A:
undetectable		 4nkvA-3lq1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 LEU A  64
PHE A  61
ILE A  99
GLY A 432
ALA A 433
 None
 1.04A 4nkvC-3lq1A:
undetectable		 4nkvC-3lq1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 LEU A  64
PHE A  61
ILE A  99
GLY A 432
ALA A 433
 None
 1.04A 4nkvD-3lq1A:
undetectable		 4nkvD-3lq1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 9 THR A 287
ILE A 313
GLY A 224
LEU A 252
LEU A 303
 None
 1.29A 4ze0A-3lq1A:
undetectable		 4ze0A-3lq1A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		5 / 11 VAL A 227
VAL A 291
VAL A 225
ILE A 283
LEU A 307
 None
 0.89A 5e4dB-3lq1A:
undetectable		 5e4dB-3lq1A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 4 LEU A 303
TYR A 366
PRO A 250
ILE A 251
 None
 1.15A 5esgA-3lq1A:
undetectable		 5esgA-3lq1A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 VAL A  75
LEU A 104
LEU A  77
ILE A  16
 None
 0.83A 5y1yA-3lq1A:
undetectable		 5y1yA-3lq1A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 GLU A  26
SER A  97
PHE A 404
LEU A 256
 None
 0.92A 5y2tB-3lq1A:
undetectable		 5y2tB-3lq1A:
undetectable