SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 3lqa HEAVY CHAIN OF ANTI
HIV FAB FROM HUMAN
21C ANTIBODY
(Homo
sapiens) 		4 / 7 PHE H  64
MET H  81
MET H  70
ALA H  79
 None
 1.09A 1linA-3lqaH:
undetectable		 1linA-3lqaH:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		4 / 8 LEU G 485
ILE G 247
HIS G 245
GLY G 259
 None
 0.72A 3b9lA-3lqaG:
undetectable		 3b9lA-3lqaG:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 12 ILE G 280
ILE G 328
ILE G 290
TRP G 333
HIS G 368
 None
 1.32A 3phaB-3lqaG:
undetectable		 3phaB-3lqaG:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3lqa HEAVY CHAIN OF ANTI
HIV FAB FROM HUMAN
21C ANTIBODY
(Homo
sapiens) 		3 / 3 PRO H 111
TYR H 102
GLY H 100
 None
 0.75A 4g2zA-3lqaH:
undetectable		 4g2zA-3lqaH:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 4qvlV-3lqaG:
undetectable
4qvlb-3lqaG:
undetectable		 4qvlV-3lqaG:
20.49
4qvlb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 4qvlH-3lqaG:
undetectable
4qvlN-3lqaG:
undetectable		 4qvlH-3lqaG:
20.49
4qvlN-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.36A 4qvmV-3lqaG:
undetectable
4qvmb-3lqaG:
undetectable		 4qvmV-3lqaG:
20.49
4qvmb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.37A 4qvmH-3lqaG:
undetectable
4qvmN-3lqaG:
undetectable		 4qvmH-3lqaG:
20.49
4qvmN-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.36A 4qvpV-3lqaG:
undetectable
4qvpb-3lqaG:
undetectable		 4qvpV-3lqaG:
20.49
4qvpb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 4qvqV-3lqaG:
undetectable
4qvqb-3lqaG:
undetectable		 4qvqV-3lqaG:
20.49
4qvqb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 4qvqH-3lqaG:
undetectable
4qvqN-3lqaG:
undetectable		 4qvqH-3lqaG:
20.49
4qvqN-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.36A 4qw0V-3lqaG:
undetectable
4qw0b-3lqaG:
undetectable		 4qw0V-3lqaG:
20.49
4qw0b-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.36A 4qw0H-3lqaG:
undetectable
4qw0N-3lqaG:
undetectable		 4qw0H-3lqaG:
20.49
4qw0N-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.34A 4qw3V-3lqaG:
undetectable
4qw3b-3lqaG:
undetectable		 4qw3V-3lqaG:
20.49
4qw3b-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 4qw3H-3lqaG:
undetectable
4qw3N-3lqaG:
undetectable		 4qw3H-3lqaG:
20.49
4qw3N-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5bxnV-3lqaG:
undetectable
5bxnb-3lqaG:
undetectable		 5bxnV-3lqaG:
20.49
5bxnb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5bxnH-3lqaG:
undetectable
5bxnN-3lqaG:
undetectable		 5bxnH-3lqaG:
20.49
5bxnN-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5cz7H-3lqaG:
undetectable
5cz7N-3lqaG:
undetectable		 5cz7H-3lqaG:
20.49
5cz7N-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.33A 5d0xV-3lqaG:
undetectable
5d0xb-3lqaG:
undetectable		 5d0xV-3lqaG:
20.49
5d0xb-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5d0xH-3lqaG:
undetectable
5d0xN-3lqaG:
undetectable		 5d0xH-3lqaG:
20.49
5d0xN-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		3 / 3 VAL G 250
SER G 483
MET G  99
 None
 0.90A 5ikqA-3lqaG:
undetectable		 5ikqA-3lqaG:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5l66V-3lqaG:
undetectable
5l66b-3lqaG:
undetectable		 5l66V-3lqaG:
20.49
5l66b-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lqa ENVELOPE
GLYCOPROTEIN GP160
(Human
immunodeficiency
virus
1) 		5 / 11 THR G 253
THR G 367
THR G 381
THR G 382
GLY G 473
 None
None
None
NAG  G2000 (-3.1A)
None
 1.35A 5l66H-3lqaG:
undetectable
5l66N-3lqaG:
undetectable		 5l66H-3lqaG:
20.49
5l66N-3lqaG:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3lqa HEAVY CHAIN OF ANTI
HIV FAB FROM HUMAN
21C ANTIBODY
(Homo
sapiens) 		5 / 12 VAL H 219
THR H 217
VAL H 223
GLY H 130
VAL H 164
 None
 0.92A 6drzA-3lqaH:
undetectable		 6drzA-3lqaH:
17.23