SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3lqc DNA POLYMERASE BETA
(Rattus
norvegicus) 		4 / 5 PHE B 278
ARG B 328
ILE B 319
GLU B 316
 None
 1.39A 1oniG-3lqcB:
undetectable
1oniH-3lqcB:
undetectable		 1oniG-3lqcB:
24.44
1oniH-3lqcB:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3lqc DNA POLYMERASE BETA
(Rattus
norvegicus) 		4 / 4 HIS B 212
VAL B 215
THR B 233
LEU B 194
 None
 1.47A 1oq5A-3lqcB:
undetectable		 1oq5A-3lqcB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqc DNA POLYMERASE BETA
(Rattus
norvegicus) 		3 / 3 ILE B 255
PHE B 235
HIS B 252
 None
 0.68A 3h0aA-3lqcB:
undetectable		 3h0aA-3lqcB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3lqc DNA POLYMERASE BETA
(Rattus
norvegicus) 		5 / 12 ARG B 182
GLY B 179
PHE B 278
TYR B 327
VAL B 313
 None
 1.25A 4ffwB-3lqcB:
undetectable		 4ffwB-3lqcB:
14.74