SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 3lqe CAPSID PROTEIN
(Norwalk
virus) 		5 / 12 LEU A 491
TYR A 492
GLY A 421
GLY A 495
LEU A 453
 None
 1.17A 3e23A-3lqeA:
undetectable		 3e23A-3lqeA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3lqe CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 HIS A 270
VAL A 230
ILE A 420
LEU A 232
 None
 0.94A 3kk6A-3lqeA:
undetectable		 3kk6A-3lqeA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3lqe CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 THR A 279
PRO A 280
VAL A 286
SER A 287
 None
 1.18A 4qknA-3lqeA:
undetectable		 4qknA-3lqeA:
22.57