SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3lqj MLL1 PHD3-BROMO
(Homo
sapiens) 		3 / 3 TRP A1768
TYR A1607
LEU A1636
 None
 0.95A 1kxhA-3lqjA:
undetectable		 1kxhA-3lqjA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3lqj MLL1 PHD3-BROMO
(Homo
sapiens) 		5 / 12 PHE A1769
MET A1762
VAL A1754
VAL A1723
LEU A1724
 None
 1.16A 3elzA-3lqjA:
undetectable		 3elzA-3lqjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3lqj MLL1 PHD3-BROMO
(Homo
sapiens) 		4 / 8 GLU A1746
LYS A1748
ASN A1751
HIS A1659
 None
 1.12A 3kp6A-3lqjA:
1.4
3kp6B-3lqjA:
1.9		 3kp6A-3lqjA:
22.11
3kp6B-3lqjA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3lqj MLL1 PHD3-BROMO
(Homo
sapiens) 		4 / 8 HIS A1628
TYR A1619
LEU A1613
LEU A1636
 None
 1.01A 3lm8B-3lqjA:
undetectable
3lm8D-3lqjA:
undetectable		 3lm8B-3lqjA:
19.92
3lm8D-3lqjA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 3lqj MLL1 PHD3-BROMO
(Homo
sapiens) 		3 / 3 LYS A1773
TRP A1777
SER A1770
 None
 1.39A 5nwwA-3lqjA:
undetectable		 5nwwA-3lqjA:
9.44