SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		4 / 7 VAL A  70
ILE A  61
MET A 171
LEU A 174
 None
 0.87A 1iepB-3lqkA:
undetectable		 1iepB-3lqkA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		4 / 6 SER A 129
THR A  94
ASN A 131
ASP A 132
 None
PO4  A 200 (-3.3A)
None
None
 1.34A 1mxdA-3lqkA:
undetectable		 1mxdA-3lqkA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		5 / 12 GLY A 113
ALA A 114
ILE A 150
ALA A  91
ILE A  90
 None
 0.97A 2nmyB-3lqkA:
undetectable		 2nmyB-3lqkA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		5 / 12 THR A 117
ILE A 128
ALA A 169
CYH A  87
VAL A   8
 None
 1.21A 3vw1D-3lqkA:
undetectable		 3vw1D-3lqkA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		4 / 4 ILE A 141
ASP A 132
ARG A 143
THR A 130
 None
 1.46A 4nx6A-3lqkA:
undetectable		 4nx6A-3lqkA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_1
(DIHYDROFOLATE
REDUCTASE)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		4 / 4 ILE A 141
ASP A 132
ARG A 143
THR A 130
 None
 1.47A 4nx7A-3lqkA:
undetectable		 4nx7A-3lqkA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3lqk DIPICOLINATE
SYNTHASE SUBUNIT B
(Bacillus
halodurans) 		3 / 3 ASN A 149
TYR A 151
CYH A  87
 None
 1.01A 5lsuB-3lqkA:
undetectable		 5lsuB-3lqkA:
23.44