SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		4 / 8 PHE A 103
LEU A  17
ILE A 128
THR A 110
 None
 0.95A 1sbrA-3lqnA:
undetectable		 1sbrA-3lqnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		4 / 6 LEU A  99
ASP A  52
LYS A  98
GLU A 126
 None
 1.23A 2vn1B-3lqnA:
undetectable		 2vn1B-3lqnA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 12 GLY A  59
ILE A  29
LEU A  60
ASP A  93
LEU A  57
 None
 1.00A 2yqzA-3lqnA:
undetectable		 2yqzA-3lqnA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		3 / 3 PHE A 115
CYH A 117
PHE A 125
 None
 1.15A 3cr5X-3lqnA:
undetectable		 3cr5X-3lqnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 11 VAL A  50
PHE A 115
SER A  62
LEU A  40
VAL A  27
 None
 1.38A 4eilA-3lqnA:
undetectable		 4eilA-3lqnA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 11 VAL A  50
PHE A 115
SER A  62
LEU A  40
VAL A  27
 None
 1.38A 4eilC-3lqnA:
undetectable		 4eilC-3lqnA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 11 VAL A  50
PHE A 115
SER A  62
LEU A  40
VAL A  27
 None
 1.39A 4eilE-3lqnA:
undetectable		 4eilE-3lqnA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  17
ALA A 133
LYS A 136
LEU A 135
ALA A 106
 None
SO4  A 163 (-3.5A)
SO4  A 166 (-2.4A)
None
None
 1.20A 4x1kA-3lqnA:
undetectable
4x1kB-3lqnA:
undetectable		 4x1kA-3lqnA:
17.06
4x1kB-3lqnA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3lqn CBS DOMAIN PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  51
GLY A 127
PHE A 115
SER A  46
GLY A  44
 FMT  A 169 ( 4.9A)
None
None
None
FMT  A 167 (-3.6A)
 1.33A 5f9zA-3lqnA:
undetectable		 5f9zA-3lqnA:
14.31