SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 7 GLU A  40
ARG A 150
LEU A 140
GLY A  94
 5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
5SP  A 500 ( 4.8A)
None
 0.87A 1mt1H-3lquA:
undetectable
1mt1K-3lquA:
undetectable		 1mt1H-3lquA:
21.66
1mt1K-3lquA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 7 GLU A  40
ARG A 150
LEU A 140
GLY A  94
 5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
5SP  A 500 ( 4.8A)
None
 0.81A 1n13D-3lquA:
undetectable
1n13E-3lquA:
undetectable		 1n13D-3lquA:
21.66
1n13E-3lquA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 8 LEU A 140
GLY A  94
GLU A  40
ARG A 150
 5SP  A 500 ( 4.8A)
None
5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
 0.80A 1n13A-3lquA:
undetectable
1n13F-3lquA:
undetectable		 1n13A-3lquA:
13.36
1n13F-3lquA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 6 GLU A  40
ARG A 150
LEU A 140
GLY A  94
 5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
5SP  A 500 ( 4.8A)
None
 0.81A 1n13H-3lquA:
undetectable
1n13K-3lquA:
undetectable		 1n13H-3lquA:
21.66
1n13K-3lquA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 7 LEU A 140
GLY A  94
GLU A  40
ARG A 150
 5SP  A 500 ( 4.8A)
None
5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
 0.80A 1n13G-3lquA:
undetectable
1n13J-3lquA:
undetectable		 1n13G-3lquA:
13.36
1n13J-3lquA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 8 GLU A  40
ARG A 150
LEU A 140
GLY A  94
 5SP  A 500 (-3.9A)
5SP  A 500 (-2.8A)
5SP  A 500 ( 4.8A)
None
 0.87A 2qqdB-3lquA:
undetectable
2qqdC-3lquA:
undetectable		 2qqdB-3lquA:
21.66
2qqdC-3lquA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		5 / 12 ILE A 122
VAL A 137
ILE A  59
VAL A  66
VAL A 171
 None
 1.13A 3iw1A-3lquA:
undetectable		 3iw1A-3lquA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 4 ASP A  34
ASP A  33
GLY A 151
THR A 157
 None
 1.38A 3tl9B-3lquA:
undetectable		 3tl9B-3lquA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 8 ASP A  42
CYH A 188
GLU A 187
ASP A  33
 5SP  A 500 ( 3.8A)
None
None
None
 1.21A 4gkiC-3lquA:
undetectable		 4gkiC-3lquA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		3 / 3 ASP A 204
VAL A  31
LEU A 160
 None
 0.59A 5e5jB-3lquA:
undetectable		 5e5jB-3lquA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		5 / 10 VAL A  29
GLY A  28
GLY A  26
LEU A  20
ALA A  19
 None
 1.06A 5vm8B-3lquA:
undetectable		 5vm8B-3lquA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 5 GLN A 143
ARG A 150
GLU A  72
ASP A  79
 None
5SP  A 500 (-2.8A)
None
None
 1.01A 5yf0A-3lquA:
undetectable		 5yf0A-3lquA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 7 ARG A  24
GLU A  25
ASP A  21
GLU A  17
 None
 1.24A 6mn5B-3lquA:
undetectable		 6mn5B-3lquA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3lqu 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Salmonella
enterica) 		4 / 6 ARG A  24
GLU A  25
ASP A  21
GLU A  17
 None
 1.34A 6mn5D-3lquA:
undetectable		 6mn5D-3lquA:
18.55