SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 10 ALA A 148
GLY A 119
GLU A  33
LEU A  29
PRO A  28
 GOL  A 190 (-4.0A)
None
None
None
None
 1.37A 1cmcA-3lqyA:
undetectable
1cmcB-3lqyA:
undetectable		 1cmcA-3lqyA:
18.82
1cmcB-3lqyA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 10 GLU A  33
LEU A  29
PRO A  28
ALA A 148
GLY A 119
 None
None
None
GOL  A 190 (-4.0A)
None
 1.36A 1mjqC-3lqyA:
undetectable
1mjqD-3lqyA:
undetectable		 1mjqC-3lqyA:
19.79
1mjqD-3lqyA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 11 GLU A  33
LEU A  29
PRO A  28
ALA A 148
GLY A 119
 None
None
None
GOL  A 190 (-4.0A)
None
 1.35A 1mjqI-3lqyA:
undetectable
1mjqJ-3lqyA:
undetectable		 1mjqI-3lqyA:
19.79
1mjqJ-3lqyA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 11 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 1.05A 2aclE-3lqyA:
undetectable		 2aclE-3lqyA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 12 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 0.98A 3e00A-3lqyA:
undetectable		 3e00A-3lqyA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 10 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 0.93A 3falA-3lqyA:
undetectable		 3falA-3lqyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 10 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 1.04A 3falC-3lqyA:
undetectable		 3falC-3lqyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		4 / 7 TYR A 138
LEU A 172
LEU A 115
PHE A  98
 None
 1.22A 3nk2X-3lqyA:
undetectable		 3nk2X-3lqyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		4 / 8 ALA A 120
LEU A  29
ALA A  36
ALA A  35
 None
 0.61A 3r9tA-3lqyA:
undetectable		 3r9tA-3lqyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		4 / 6 ASP A  13
THR A 122
ILE A 126
PHE A  14
 None
 1.02A 4acbC-3lqyA:
5.0		 4acbC-3lqyA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 9 PHE A  14
SER A  80
ALA A  34
GLY A  39
ALA A 171
 None
 1.35A 4l6va-3lqyA:
undetectable
4l6vf-3lqyA:
undetectable		 4l6va-3lqyA:
15.06
4l6vf-3lqyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 9 LEU A 103
ALA A 132
ASP A 135
ILE A  95
THR A 101
 None
 1.15A 4njtD-3lqyA:
undetectable		 4njtD-3lqyA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		4 / 6 THR A 130
THR A 149
HIS A 165
LEU A 172
 None
GOL  A 190 (-4.6A)
GOL  A 190 (-3.8A)
None
 1.12A 4pgfA-3lqyA:
3.0		 4pgfA-3lqyA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 11 VAL A 118
GLY A 119
ASP A 145
ALA A 143
LEU A  42
 None
 1.03A 5x6yA-3lqyA:
undetectable		 5x6yA-3lqyA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 10 VAL A 118
GLY A 119
ASP A 145
ALA A 143
LEU A  42
 None
 1.10A 5x6yB-3lqyA:
undetectable		 5x6yB-3lqyA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 11 VAL A 118
GLY A 119
ASP A 145
ALA A 143
LEU A  42
 None
 0.99A 5x6yC-3lqyA:
undetectable		 5x6yC-3lqyA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 12 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 0.99A 6a5yD-3lqyA:
undetectable		 6a5yD-3lqyA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3lqy PUTATIVE
ISOCHORISMATASE
HYDROLASE
(Oleispira
antarctica) 		5 / 12 ALA A 146
ALA A  35
GLN A  38
ALA A 182
ILE A  77
 None
 1.05A 6a60D-3lqyA:
undetectable		 6a60D-3lqyA:
16.93